Biomedical subjects

P Hanggi

Publications and source records attributed to P Hanggi.

At least 19 recordsLinked to original sources

PubMed2000

Strong coupling theory for driven tunneling and vibrational relaxation

We investigate on a unified basis tunneling and vibrational relaxation in driven dissipative multistable systems described by their N lowest lying unperturbed levels. By use of the discrete variable representation we derive a set of coupled non-Markovian master equations. We present analytical treatments that describe the dynamics in the regime of strong system-bath coupling. Our findings are corroborated by "ab initio" real-time path integral calculations.

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PubMed2000

Surmounting oscillating barriers

Thermally activated escape over a potential barrier in the presence of periodic driving is considered. By means of novel time-dependent path-integral methods we derive asymptotically exact weak-noise expressions for both the instantaneous and the time-averaged escape rate. The agreement with accurate numerical results is excellent over a wide range of driving strengths and driving frequencies.

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PubMed2000

Drift ratchet

We consider a silicon wafer, pierced by millions of identical pores with periodically varying diameters but without spatial inversion symmetry (ratchet profile). When a liquid is periodically pumped back and forth through the pores, our theory predicts a net transport of suspended micrometer-sized particles (drift ratchet). The direction of this particle current depends very sensitively on the size of the particles. For typical parameter values of the experiment, two different types of particles at an initially homogeneous 1:1 mixture are spatially separated with a purity beyond 1:1000 on a time scale of a few hours in comparably large quantities. This result is due to the highly parallel architecture of the device. The experimental realization of the setup, presently under construction, thus appears to be a promising new particle separation device, possibly superior to existing methods for particles sizes on the micrometer scale.

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PubMed2000

Driven tunneling dynamics: Bloch-Redfield theory versus path-integral approach

In the regime of weak bath coupling and low temperature we demonstrate numerically for the spin-boson dynamics the equivalence between two widely used but seemingly different roads of approximation, namely, the path-integral approach and the Bloch-Redfield theory. The excellent agreement between these two methods is corroborated by an efficient analytical high-frequency approach: it well approximates the decay of quantum coherence via a series of damped coherent oscillations. Moreover, a suitably tuned control field can selectively enhance or suppress quantum coherence.

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PubMed2000

Amorphous thin film growth: minimal deposition equation

A nonlinear stochastic growth equation is derived from (i) the symmetry principles relevant for the growth of vapor deposited amorphous films, (ii) no excess velocity, and (iii) a low-order expansion in the gradients of the surface profile. A growth instability in the equation is attributed to the deflection of the initially perpendicular incident particles due to attractive forces between the surface atoms and the incident particles. The stationary solutions of the deterministic limit of the equation and their stability are analyzed. The growth of the surface roughness and the correlation length of the moundlike surface structure arising from the stochastic growth equation is investigated.

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PubMed2000

Theory of controlling stochastic resonance

The concept of controlling stochastic resonance has been recently introduced [L. Gammaitoni et al., Phys. Rev. Lett. 82, 4574 (1999)] to enhance or suppress the spectral response to threshold-crossing events triggered by a time-periodic signal in background noise. Here, we develop a general theoretical framework, based on a rate equation approach. This generic two-state theory captures the essential features observed in our experiments and numerical simulations.

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PubMed2000

Stochastic resonance driven by time-modulated correlated white noise sources

We analyze the effects caused by the simultaneous presence of correlated additive and multiplicative noises for stochastic resonance. Besides the standard potential modulation we also consider a time-periodic variation of the correlation between the two noise sources. As a foremost result we find that stochastic resonance, as characterized by the signal-to-noise ratio and the spectral amplification, becomes characteristically broadened. The broadening can be controlled by varying the relative phase shift between the two types of modulation force.

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PubMed2000

Iterative algorithm versus analytic solutions of the parametrically driven dissipative quantum harmonic oscillator

We consider the Brownian motion of a quantum-mechanical particle in a one-dimensional parabolic potential with periodically modulated curvature under the influence of a thermal heat bath. Analytic expressions for the time-dependent position and momentum variances are compared with results of an iterative algorithm, the so-called quasiadiabatic propagator path-integral algorithm. We obtain good agreement over an extended range of parameters for this spatially continuous quantum system. These findings indicate the reliability of the algorithm also in cases for which analytic results may not be available a priori.

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PubMed2000

Nonlinear stochastic resonance: the saga of anomalous output-input gain

We reconsider stochastic resonance (SR) for an overdamped bistable dynamics driven by a harmonic force and Gaussian noise from the viewpoint of the gain behavior, i.e., the signal-to-noise ratio (SNR) at the output divided by that at the input. The primary issue addressed in this work is whether a gain exceeding unity can occur for this archetypal SR model, for subthreshold signals that are beyond the regime of validity of linear response theory: in contrast to nondynamical threshold systems, we find that the nonlinear gain in this conventional SR system exceeds unity only for suprathreshold signals, where SR for the spectral amplification and/or the SNR no longer occurs. Moreover, the gain assumes, at weak to moderate noise strengths, rather small (minimal) values for near-threshold signal amplitudes. The SNR gain generically exhibits a distinctive nonmonotonic behavior versus both the signal amplitude at fixed noise intensity and the noise intensity at fixed signal amplitude. We also test the validity of linear response theory; this approximation is strongly violated for weak noise. At strong noise, however, its validity regime extends well into the large driving regime above threshold. The prominent role of physically realistic noise color is studied for exponentially correlated Gaussian noise of constant intensity scaling and also for constant variance scaling; the latter produces a characteristic, resonancelike gain behavior. The gain for this typical SR setup is further contrasted with the gain behavior for a "soft" potential model.

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PubMed2000

Stochastic dynamics of time correlation in complex systems with discrete time

In this paper we present the concept of description of random processes in complex systems with discrete time. It involves the description of kinetics of discrete processes by means of the chain of finite-difference non-Markov equations for time correlation functions (TCFs). We have introduced the dynamic (time dependent) information Shannon entropy S(i)(t) where i=0,1,2,3,ellipsis, as an information measure of stochastic dynamics of time correlation (i=0) and time memory (i=1,2,3,ellipsis). The set of functions S(i)(t) constitute the quantitative measure of time correlation disorder (i=0) and time memory disorder (i=1,2,3,ellipsis) in complex system. The theory developed started from the careful analysis of time correlation involving dynamics of vectors set of various chaotic states. We examine two stochastic processes involving the creation and annihilation of time correlation (or time memory) in details. We carry out the analysis of vectors' dynamics employing finite-difference equations for random variables and the evolution operator describing their natural motion. The existence of TCF results in the construction of the set of projection operators by the usage of scalar product operation. Harnessing the infinite set of orthogonal dynamic random variables on a basis of Gram-Shmidt orthogonalization procedure tends to creation of infinite chain of finite-difference non-Markov kinetic equations for discrete TCFs and memory functions (MFs). The solution of the equations above thereof brings to the recurrence relations between the TCF and MF of senior and junior orders. This offers new opportunities for detecting the frequency spectra of power of entropy function S(i)(t) for time correlation (i=0) and time memory (i=1,2,3,ellipsis). The results obtained offer considerable scope for attack on stochastic dynamics of discrete random processes in a complex systems. Application of this technique on the analysis of stochastic dynamics of RR intervals from human ECG's shows convincing evidence for a non-Markovian phenomemena associated with a peculiarities in short- and long-range scaling. This method may be of use in distinguishing healthy from pathologic data sets based in differences in these non-Markovian properties.

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PubMed2000

Surmounting oscillating barriers: path-integral approach for weak noise

We consider the thermally activated escape of an overdamped Brownian particle over a potential barrier in the presence of periodic driving. A time-dependent path-integral formalism is developed which allows us to derive asymptotically exact weak-noise expressions for both the instantaneous and the time-averaged escape rate. Our results comprise a conceptually different, systematic treatment of the rate prefactor multiplying the exponentially leading Arrhenius factor. Moreover, an estimate for the deviations at finite noise strengths is provided and a supersymmetry-type property of the time-averaged escape rate is verified. For piecewise parabolic potentials, the rate expression can be evaluated in closed analytical form, while in more general cases, as exemplified by a cubic potential, an action-integral remains to be minimized numerically. Our comparison with very accurate numerical results demonstrates an excellent agreement with the theoretical predictions over a wide range of driving strengths and driving frequencies.

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PubMed1994