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Biomedical subjects

P Hawker

Publications and source records attributed to P Hawker.

9 recordsLinked to original sources
PubMed1992

Hydroxyapatite-coated implants in maxillofacial prosthetics.

The use of implants provides a secure, comfortable, and emotionally satisfactory attachment of the patient to the prosthesis. It is anticipated that patients who are willing to undergo placement of implants would have a greater commitment to continued use of their prostheses. Clearly, there is a greater affinity between a patient and his or her prosthesis when the attachment is an intimate one. The use of implants, then, could reverse functional deficiencies and raise the quality of the patient's post-disease life.

Denture Design↗
PubMed1989

Peptic ulcer disease.

Many of the drugs available for treating peptic ulcer disease have a series of possible overlapping actions on various stages both of acid suppression and mucosal defence, but in certain situations one drug may be better than another. More research is needed to clarify the aetiology of peptic ulcer disease so that treatment can be improved.

Anti-Ulcer Agents↗
PubMed1986

A randomized controlled trial of variceal compression as an adjunct to endoscopic variceal sclerosis.

Endoscopic variceal sclerosis is effective at eradicating oesophageal varices and prolonging survival, but early rebleeding before varices have been obliterated remains a problem. A randomized controlled trial was therefore conducted to determine whether more rapid variceal obliteration and hence a lower morbidity and mortality in the first month could be achieved by compressing the varices after the first injection of sclerosant. Forty patients bleeding from previously untreated varices were studied. There was no demonstrable benefit from post-sclerosis variceal compression in terms of early death from rebleeding (compression, 3 of 19; no compression, 3 of 21 in the first month), total number of patients rebleeding (compression, 5 of 19; no compression, 6 of 21 in the first month), or speed of variceal obliteration (percentage of variceal columns obliterated at 1 month: compression, 13%; no compression, 26%). This study shows that post-sclerosis variceal compression by means of the Williams overtube and Sengstaken tamponade does not improve the efficacy of endoscopic variceal sclerosis.

Clinical Trials as Topic↗
PubMed1983

Entero-enteric fistula complicating Crohn's disease.

We have reviewed our experience with, and management of, entero-enteric fistula in Crohn's disease between 1970 and 1980 (inclusive). Thirty-three patients (20 of them female) came to our unit with entero-enteric fistulas, representing one-third of all Crohn's fistulas seen during those years. Entero-enteric fistulas gave few symptoms and their precise identification was not important in clinical management. The presence of the fistula itself is not an indication for operation and treatment should be directed towards the active or stenotic disease and not to the entero-enteric fistula. Therefore, radiological examination is important only to identify the extent of underlying disease.

Adolescent↗
PubMed1982

Enterovaginal fistulas associated with Crohn's disease.

Our experience in the management of 16 enterovaginal fistulas complicating Crohn's disease leads us to believe that such fistulas usually arise from active rectal disease and, despite being evident clinically, are difficult to confirm endoscopically or radiologically. Patients with few symptoms can be managed conservatively. Surgical repair protected by diversion may have a place in management, but most with severe symptoms will require excision of the intestine from which the fistula is arising.

Adult↗