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Biomedical subjects

P Hee

Publications and source records attributed to P Hee.

6 recordsLinked to original sources
PubMed1982

Nontoxic goitre. I. Surgical complications and longterm prognosis.

In the period 1960-1968, 182 patients underwent surgery for nontoxic goitre at Roskilde County Hospital. The total frequency of peroperative complications was 10%. After a mean interval of 16.4 years, 162 of the patients could be followed up and 86% expressed satisfaction with the result of thyroid surgery. Only two patients (1.2%) had longterm sequelae in the form of voice problems and calcium requirements. No thyroid cancer appeared in the observation period. In 19% there was recurrence of benign goitre. The interval to recurrence was 1 month to 14 years.

Adolescent↗
PubMed1982

Nontoxic goitre. II. A study of the pituitary-thyroid axis in 14 recurrent cases.

Of 182 patients operated on for nontoxic goitre, 162 could be followed up after a mean period of 16.4 years. In 31 (19%) of the 162 patients the goitre had recurred. No patient had received regular thyroid-substitution therapy postoperatively. Of the 31 recurrences, 14 had not been treated at the time of follow-up. These 14 patients were matched with controls (without recurrence) from the original series, according to sex, age and time of operation. Thyroid-stimulating hormone (TSH), serum thyroxin (T4), triiodothyronine (T3) and thyroid antibodies were determined in both groups. There were no intergroup differences as regards TSH and T4, which were within normal range. T3 values were elevated in both groups, but were significantly higher in the patients with goitre recurrence than in their control group. Routine postoperative use of thyroid-substitution therapy is not supported by the findings in this study.

Adult↗