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Biomedical subjects

P Heeg

Publications and source records attributed to P Heeg.

At least 19 recordsLinked to original sources
PubMed1997

[A Salmonella epidemic by Salmonella subspecies II 4,12,12,27:b:- at the University Hospital of Tübingen in April 1996].

In April 1996 four patients at the University Hospital of Tübingen became ill with diarrhoea at short intervals; one of the patients also suffered from fever. From stool samples of all four patients Salmonella subspecies II 4,12,27:b:- was isolated; from the patient who had fever the pathogen was also isolated from one blood culture. The patients were treated at different wards of the hospital. All four patients suffered from underlying diseases. In the course of a microbiological examination of the central kitchen staff of the hospital Salmonella subspecies II 4,12,27:b:- was isolated from a stool sample of one of the employees. No contact to cold blooded animals, no travel abroad and no symptoms of gastroenteritis were reported by the employee. When the employee had been temporarily suspended no further Salmonella infections occurred.

Adult↗
PubMed1996

Disinfection of pumice.

Pumice is a potential source of infection for the dental technician and of cross-contamination between different dentures and patients. In this study, the number of microorganisms in two different combinations of pumice and disinfectant was compared with a conventional mixture of pumice and water. The results revealed that under practical conditions the mix of Steribim (pumice containing benzoic acid added by the manufacturer) with water reduced the number of bacteria by 99% compared with a mix of a conventional pumice and water. The addition of an antiseptic product that contained octenidine as active agent to conventional pumice reduced the number of microorganisms by 99.999%.

Anti-Infective Agents, Local↗
PubMed1995

Ethics and the decision making process.

Decision making in a clinical setting is influenced by each individual's ethical and moral principles. This paper considers a case study of a man with Parkinson's disease. The morals and principles held by the participants within the decision making process are defined, described and schematically represented according to their role in the process. The author concludes that this case study has changed her attitude to clinical decision making processes.

Aged↗
PubMed1994

Automated processing of endoscopic surgical instruments.

This paper deals with the requirements for automated processing of endoscopic surgical instruments. After a brief analysis of the current problems, solutions are discussed. Test-procedures have been developed to validate the automated processing, so that the cleaning results are guaranteed and reproducable. Also a device for testing and cleaning was designed together with Netzsch Newamatic and PCI, called TC-MIC, to automate processing and reduce manual work.

Automation↗
PubMed1994

[Infections caused by Flavobacterium meningosepticum in patients in a neonatal intensive care unit].

During a period of three and a half months 7 neonates from a neonatal intensive care unit became infected by F. meningosepticum, serotype B. The pathogens could be isolated from the tracheal secretions and--less frequently--from throat swabs, gastric juice and nose swabs. Environmental sampling led to the isolation of F. meningosepticum from the humidification fluid of the respirator, from vaporizers as well as from the artificial ventilation tubing. F. mengingosepticum was found in the water of humidifiers from 3 children, who developed neither a colonization nor an infection. In a number of cases the patients' environment was contaminated with F. meningosepticum prior to colinization or infection. Nearly identical resistance patterns against the antibiotics tested, could be demonstrated for the isolated strains. The primary source of infection could not be identified, it is supposed however that the index patient had been admitted to the hospital nine months before. A strict hygienic policy, like consequently performed hand hygiene, adequate processing of ventilation equipment and application of sterile tubings led to extinction of the infections. During subsequent environmental controls, F. meningosepticum could not be isolated.

Anti-Bacterial Agents↗
PubMed1992

Evaluation of the efficacy of surgical hand disinfection following a reduced application time of 3 instead of 5 min.

The guidelines of the German Society for Hygiene and Microbiology for the evaluation of disinfectants suggest an application time of 5 min for surgical scrub products. In a comparative investigation, which included the more important basic substances and agents, tests were carried out to investigate whether it was possible to reduce the application time to 3 min without losing efficiency in both the immediate as well as the prolonged effect of bacterial reduction. It was found that this could be achieved by certain products, depending on the formula and type of active substance. Thus, a reduced application time of 3 min can be considered for the evaluation of surgical scrub disinfectants for national and international guidelines.

1-Propanol↗
PubMed1991

[Disinfection of dental impressions].

The need for disinfection of dental impressions is generally postulated. While many disinfectants for elastomeric impression materials have been recommended for at least ten years, several authors recently described suitable disinfectants for alginate impressions. Disinfectants for reversible hydrocolloid materials are in the phase of practical testing, and show promising first results. Under practical and scientific aspects further investigations are necessary to evaluate standards and standardized testing procedures.

Alginates↗
PubMed1990

[Antisepsis of mucous membranes--current status and aspects of future development].

The mucous membranes colonized by high numbers of microorganisms play a major role as a source of nosocomial infections. According to clinical requirements it seems reasonable to distinguish three modes of application of antiseptics: 1. single prophylactic (prior to mucosa-penetrating interventions), 2. repeated periodical (wound care, treatment of oral cavity in intubated patients, decontamination of granulocytopenic patients), 3. therapeutic (local mucosal infections) including treatment of carriers to prevent transmission and spread of pathogens. Active agents commonly in use are PVP-iodine, cation-active detergents (e.g. chlorhexidine), oxygen-releasing compounds and organic mercury compounds. Presently chlorhexidine and PVP-iodine are the most frequently applied of these antiseptics while the organic mercury compounds are less important because of limited efficacy, toxicological and ecological problems. Preliminary data from investigations using a newly developed antiseptic, octenidine, a bispyridine compound, demonstrate reduction factors comparable to those obtained by PVP-iodine. Yet no standardized test methods for the efficacy of different substances and methods of application have been established.

Colony Count, Microbial↗
PubMed1990

[Microbiology studies of intra- and postoperative autotransfusion in orthopedics].

In order to determine the risk of bacterial contamination of blood during autotransfusion, blood samples were taken from the autotransfusion system of 25 consecutive total hip replacements at various stages and at different times (9 samples per patient). According to the same principle, samples were taken from the identical system after processing the postoperative drainage blood. Since the danger of contamination depends on the quality of the air which is sucked into the autotransfusion system along with the blood, we also measured the amount of bacteria in the air in two different operating rooms: Horizontal laminar air flow was provided for 20, conventional ventilation for a further 5 operations. Evaluation of airborne contamination in the operating rooms showed at most 656 cfu/m3 in the conventionally ventilated room and at most 344 cfu/m3 in the room with laminar air flow. Micrococci and peptococci were cultivated from 2 samples out of 225. The isolates were derived from 2 different patients (1 in the LAF-OR, 1 in the conventionally ventilated OR); both samples were taken from the retransfusion bag towards the completion of surgery. From these results we conclude that even in a conventionally ventilated operating room during primarily aseptic surgery intraoperative autotransfusion does not involve an increased risk of infection. This also applies to the retransfusion of processed blood from Redon drainages using the identical autotransfusion set.

Air Microbiology↗