[The gluttony enzyme and the Story of O].
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Biomedical subjects
Publications and source records attributed to P Henri.
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B-Flow is a new imaging technique which uses General Electric's Digitally Encoded Ultrasound technology to provide direct visualization of blood echoes in grey-scale imaging. This allows simultaneous imaging of blood flow and vessel walls with a high frame rate and high spatial resolution without information on velocity and direction. This promising technique which improves early detection of vascular disease could modify our routine practice in a near future.
We have observed transition radiation at optical wavelengths, emitted by 3-13-MeV electrons interacting with a diffraction grating. Near the direction of specular reflection we observed broadband radiation with the same properties as optical transition radiation from a flat surface. In addition, at large angles with respect to this direction and for low angles of incidence of the electrons on the grating surface, we observed the emission of quasimonochromatic radiation. This grating transition radiation may offer an alternative method for production of quasimonochromatic radiation in the far-infrared to mm wavelength range.
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We report the case of a 26 year old woman who presented a Henoch Schönlein purpura at 13 weeks' gestation. IgA glomerulonephritis without pejoratif feature was confirmed by renal biopsy. Corticosteroid therapy was unsuccessful on nephrotic syndrome. At 25 weeks' gestation foetal death occurred followed by a rapid development of end stage renal failure.
OBJECTIVE: To assess the clinical value of quantitative assay of leukocyte cytomegalovirus antigen (LCA) in the management of immunodepressed patients. METHODS: Thirty-three kidney transplant recipients followed a weekly follow-up protocol during the first 3 months after transplantation. LCA was compared with cytomegalovirus (CMV) detection in blood using fibroblast cell culture and with serology tests. LCA was expressed in number of positive cells per 2.10(5) leukocytes, detected by immunofluorescence with a specific monoclonal antibody directed against the pp65 antigen. The standard culture method and a rapid centrifuge method were used for blood samples. The serum level of anti CMV antibodies was determined by ELISA. RESULTS: CMV infection defined as positive viraemia and/or positive serology tests was diagnosed in 22 of the 33 patients. LCA was detected in 20 patients, including all those with clinical signs of infection. Serology was the only method giving a positive diagnosis in 2 patients and was negative in 3 infections positive for LCA. Viraemia was negative in 2 patients positive for LCA. LCA was detected in 60 of the 65 blood samples with a positive viraemia test and in 46 of the 165 negative samples (sensitivity 92% and specificity 72%). Quantitatively, LCA in samples taken from patients with clinical signs was higher than that in samples taken from asymptomatic patients (51 +/- 5 versus 20 +/- 2, p < 0.001). In addition, LCA was detected a mean 7.6 +/- 4 days before significant changes in serology tests, 2.2 +/- 1.6 days before the viraemia and 7.1 +/- 1 days before clinical manifestations. CONCLUSION: Leukocyte cytomegalovirus antigen gives a sensitive means of early positive diagnosis. The quantified level illustrates the patient's risk of infection. This new method is a very helpful tool in following renal transplantation recipients.
Two cases reports of interferon alpha-associated nephropathy are reported. The first observation is a membranoproliferative glomerulonephritis and the second a renal microangiopathy. The different cases in the literature are reviewed and the pathophysiology is discussed.
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The antibiotic sensitivity of 43 strains of Pseudomonas and the minimal inhibitory concentration of mercurial derivatives (5 mineral salts and 4 organics compounds) and of silver nitrate to these microorganisms have been studied. Twelve of these strains were P. aeruginosa of hospital origin, and 31 were Pseudomonas from surface water. Resistance against these inhibitory substances let us to established some connections between the different strains. Some strains were selected to transfer resistance markers by conjugation.
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