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Biomedical subjects

P Hensleigh

Publications and source records attributed to P Hensleigh.

8 recordsLinked to original sources
PubMed2006

First aid for obstetric haemorrhage: the pilot study of the non-pneumatic anti-shock garment in Egypt.

OBJECTIVE: To compare the effect of non-pneumatic anti-shock garment (NASG) on blood loss from obstetric haemorrhage with standard management of obstetric haemorrhage. DESIGN: Observational study of consecutive obstetric haemorrhage cases before and after introduction of the NASG. SETTING: Four tertiary care maternity facilities in Egypt. SAMPLE: The sample consisted of women with obstetric haemorrhage and signs of shock and the entry criteria were: >750 mL of blood loss and either pulse of >100 beats per minute or systolic blood pressure of <100 mmHg. A total of 158 women were in the preintervention group and 206 in the postintervention group. METHODS: All the women with haemorrhage meeting the eligibility criteria were treated according to the standard protocol for 4 months (May-August 2004); blood loss was measured and recorded. The NASG was then introduced, and all the women meeting the eligibility criteria were treated according to the standard haemorrhage protocol plus the NASG for 4 months (September-December 2004). MAIN OUTCOME MEASURES: Measured blood loss collected in a closed-end, graduated, plastic, under buttocks collection drape. RESULTS: Median measured blood loss in the drape following study entry was 50% lower in those treated with the NASG (250 versus 500 mL, P < 0.001). There was also a non-statistically significant decrease in morbidity and mortality. CONCLUSIONS: This is the first comparative study of the NASG with a standard obstetric haemorrhage treatment protocol. The NASG shows promise for management of obstetric haemorrhage, particularly in lower resource settings. Larger studies will be needed to determine if the NASG contributes to statistically significant decreases in morbidity and mortality.

Adult↗
PubMed1988

Major congenital anomalies in infants and glycosylated hemoglobin levels in insulin-requiring diabetic mothers.

Glycosylated hemoglobin levels were obtained in 133 diabetic pregnancies. Nongestational diabetic mothers delivered of infants with major congenital anomalies had significantly higher glycosylated hemoglobin levels than the remaining nongestational diabetic mothers (P less than .001). The higher a mother's glycosylated hemoglobin level, the higher her risk of having a severely affected infant was. The positive predictive value for a nongestational diabetic mother having an infant with severe congenital anomalies was 26% if the glycosylated hemoglobin level was greater than or equal to 11%, 40% if the level was greater than or equal to 12%, and 56% if the level greater than or equal to 13%. However, high glycosylated hemoglobin levels in insulin-requiring gestational diabetic mothers were not predictive of major congenital anomalies.

Congenital Abnormalities↗
PubMed1986

Antepartum external cephalic version under tocolysis.

Reported are 172 patients considered for external cephalic version at gestational age greater than 37 weeks. Their outcome was compared with 40 similar patients in whom external version was not attempted. One hundred fifty-eight patients had attempted version, and success was achieved in 122 (77%). Intrapartum vertex presentation occurred in 12% of the control population and in 77% of the version patients. Cesarean section was performed in 80% of the control patients and in 32% of the version patients. There were no maternal or fetal complications directly attributable to external cephalic version. Antepartum external cephalic version under tocolysis is associated with a high success rate, an acceptably low rate of complications, and a decreased incidence of cesarean section for breech presentation at term.

Adult↗
PubMed1985

Paradoxical response to intravenous terbutaline.

Marked uterine hypertonus was observed in our patient subsequent to the intravenous administration of terbutaline prior to an attempt at external cephalic version. The proximity of hypertonus to terbutaline infusion and the absence of other stimuli suggests that this was a paradoxical response to terbutaline.

Adult↗
PubMed1977

Effects of behavioral and medical variables on fetal growth retardation.

Cigarette smoking, indulging in certain drugs, restricting maternal weight gain in pregnancy, failing to obtain sufficient prenatal care, undertaking pregnancy at too early or too advanced on age, and being underweight for height at conception have in the past been identified with either increased premature births or births of term infants with fetal growth retardation. Each of these seven variables contains an element of maternal choice and has therefore been labeled by us as a behavioral variable. The combined group of mothers having these seven behavior variables was compared to a smaller group of mothers with medical complications and to a control group of mothers with neither behavioral nor medical variables. In the control group, there was a remarkably low incidence of premature births under 37 weeks (1 per cent), of term infants who had short body lengths at birth for their fetal ages (1.4 per cent), and of low-birth-weight infants (1 per cent). As the number of seven behavioral variables increased from none to three or more per pregnancy, the incidences of premature births, of short-for-dates term infants, and of low-birth-weight infants increased proportionately and significantly. The incidences of these seven behavioral variables, occurring either singly or in combination, were inverse to the mothers' socioeconomic status. However, the incidences of premature births, of growth-retarded term infants, and of low-birth-weight infants were high among mothers who had two or more behavioral variables in their pregnancies regardless of the mothers' socioeconomic status. The group of mothers with behavioral variables in comparison to the smaller group of mothers with medical complications had lower incidences but higher absolute numbers of premature infants, of growth-retarded term infants, and of low-birth-weight infants. Mothers who had medical complications as well as behavioral variables had more growth-retarded term infants than mothers with medical complications alone.

Behavior↗
PubMed1976

Socioeconomic factors in relation to fetal growth in white infants.

Over 1,200 white mothers who were delivered consecutively at this medical center were classified in four different socioeconomic classes according to family affluence and occupations of the heat of the household. The frequency of low-birth-weight infants was highest in the lowest socioeconomic class. The high incidence of LBW infants in the lowest socioeconiomic group was not affected by any significant increase in number of mothers with medical problems or medical complications of pregnancy; it was dependent on the large number of mothers who were involved in four specific practices, largely of their own choosing, including low-weight gains, cigarette smoking, use of certain drugs during pregnancy, and refraining from all prenatal care. Mothers in the four socioeconomic classes who were not involved with these four specific practices (smoking, etc.) and whose pregnancies were free of medical problems and complications had uniformly low incidences of LBW infants and the mean birth weights of their infants were uniformly high and not significantly different. Unfavorable outcome of pregnancy with respect to fetal growth in this study appeared to depend less directly on socioeconomic circumstances than on the four specific maternal practices listed above.

Body Weight↗