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P Herath

Publications and source records attributed to P Herath.

4 recordsLinked to original sources
PubMed2001

Visual recognition: evidence for two distinctive mechanisms from a PET study.

In this study, we examined the hypothesis that two distinct sets of cortical areas subserve two dissociable neurophysiological mechanisms of visual recognition. We posited that one such mechanism uses category specific cues extractable from the viewed pattern for the purpose of recognition. The other mechanism matches the pattern to be recognized with a pre-encoded memory representation of the pattern. In order to distinguish the cortical areas active in these two strategies, we measured changes in regional cerebral blood flow (rCBF) with positron emission tomography (PET) and (15)O Butanol as the radiotracer. Ten subjects performed pattern recognition tasks based on three different short-term memory conditions and a condition based on visual categories of the patterns. When subjects used representations of the patterns held in short-term memory for the purpose of recognition, the precunei were bilaterally activated. Recognition based on visual categories of the patterns activated the right (R) angular gyrus, left (L) inferior temporal gyrus, and L superior parieto-occipital cortex. These findings demonstrate that the R angular gyrus, the L inferior temporal gyrus, and the L superior parieto-occipital cortex are associated with recognition of patterns based on visual categories, whereas recognition of patterns using memory representations is associated with the activity of the precunei. This study is the first to show functional dual dissociation of active cortical fields for different mechanisms of visual pattern recognition.

Adult↗
PubMed2001

Neural correlates of dual task interference can be dissociated from those of divided attention: an fMRI study.

When people perform two tasks simultaneously, the tasks are often executed slower and with more errors than when they are carried out as single tasks. This is called dual task interference. With functional magnetic resonance imaging (fMRI), we show that concurrently performed visual and somatosensory reaction time (RT) tasks engage almost identical volumes of cortical and subcortical motor structures. Moreover, dual RT tasks engaged additional cortical regions that are not activated by the component RT tasks had they been performed as single tasks. When the inter-stimulus interval was <300 ms, the first task interfered with the second, and a field in the right inferior frontal gyrus (RIFG) appeared with activity correlated with the increased RT to the second stimulus. This activation was spatially distinct from the cortical activity of the main effect of dual task performance. Thus, the performance of single RT tasks, dual RT tasks and dual RT tasks that interfere differ psychophysically and in the brain structures subserving these tasks. A short occupancy of the common motor structures can explain the interference effect. The increased activity of the RIFG correlated with the interference effect is very likely to be a specific outcome of situations where two concurrent tasks interfere with each other. The brain appears to recruit the RIFG for a subsequent (delayed) response when there is interference between dual tasks.

Adult↗