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Biomedical subjects

P Hermant

Publications and source records attributed to P Hermant.

4 recordsLinked to original sources

[Evaluation of advanced non-small-cell lung cancer (ANSCLC) chemotherapy in routine practice].

BACKGROUND: Patients in ANCCLC chemotherapy-trials are not representative of the general lung cancer population. The purpose of this study was to describe the ANCCLC population routinely treated by chemotherapy in a general hospital, and to assess the results of chemotherapy in this population. METHODS: All newly diagnosed IIIB/IV ANCCLC chemotherapy-treated patients over a three-year period were prospectively assessed for response rate, toxicity and survival. RESULTS: Seventy seven patients (70% stage IV, 69% PS 1/0, 30% with cerebral metastases, 60% ineligible for major lung trials) received first-line chemotherapy (cisplatine or paraplatine with vinorelbine) with tumor control in 31 (40%) and symptom improvement in 20 (26%) patients. 17 (22%) patients experienced febrile neutropenia. 33 (43%) patients received second line chemotherapy (gemcitabine) with tumor control in 12 (36%) and symptom improvement in 9 (27%) patients. Overall median survival was 7 months and 30% patients were alive at 1 year. CONCLUSIONS: Routinely ANCCLC chemotherapy-treated patients in our center have poor prognostic factors and many comorbidities. Chemotherapy results in tumor control in 43% patients, - of whom two thirds have symptom improvement -, with a high rate of febrile neutropenia.

Aged↗

[Primary pulmonary choriocarcinoma].

The authors report a case of a young woman who had been found to have a chorio-carcinoma in the apex of the left lower lobe, following a major and recurrent haemothorax. A study of her past history and a gynaecological examination had not revealed any evidence of a primary tumour. Following this observation the possibility of a primary pulmonary carcinoma was considered and also the usual aetiological hypothesis, namely the migration of trophoblastic cells during an abortion even followed by a normal pregnancy and a degeneration after several years of these cells blocked in the pulmonary capillaries.

Adult↗

[An unusual case in Belgium of intestinal myiasis due to Eristalis tenax].

We report an unusual case in Belgium of indigenous intestinal myiasis caused by Eristalis tenax during canicular summer 2003 in a 36 year old man living in Belgium. This patient complain near its general practitioner about diarrhea and intestinal rumbles. Larvae emitted on several occasions were identified as Eristalis tenax larvae. Socio-economical status of the patient and atmospheric conditions seems to be related to this observation. Clinical evolution has been spontaneously and quickly positive. An empirical treatment with an association of metronidazole and nifuroxazide was however prescribed.

Adult↗