Rhabdomyolysis and acute theophylline overdose.
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Acute Disease↗
Biomedical subjects
P I Andersen
Publications and source records attributed to P I Andersen.
[A centrifugal pump used as a support of left ventricular pumping function after extracorporeal circulation].
The first Danish employment of a centrifugal pump for relief of the left ventricle after open heart surgery is presented. A man aged 72 years with three-vessel coronary arteriosclerosis was submitted to a coronary by-pass operation. At the conclusion of the operation, the pumping capacity of the heart was found to be so reduced that it was not possible to maintain an adequate minute-volume without support from a mechanical pump. The circulation in this patient was supported for four hours by means of an outflow catheter from the left atrium and an inflow catheter in the ascending aorta. After this, the patient's own heart could achieve the necessary minute-volume. The remainder of the postoperative course was uncomplicated.
Aged↗
[Rational hemotherapy. Indications, complications and practical performance].
Employment of allogenic blood products involves the risk of a series of complications in the recipient: transfusion-transmitted disease, immune suppression, immunological transfusion reactions and coagulopathy. Hepatitis C is the most common transfusion-transmitted infection with a post-transfusion incidence of 2-4%. Transfusion-transmitted AIDS plays a quantitatively lesser role but the course of the condition is frequently fatal. The duration of the period during which a HIV-sero-negative individual is potentially infectious is uncertain. After blood transfusion, the immune apparatus is suppressed, probably on account of the leukocyte content of the blood transfusion. These disturbances in immune function increase the risk of infection and possibly the frequency of recurrence of cancer after operative treatment of a series of neoplastic diseases. Coagulopathy after blood transfusion may be related primarily to the number of transfusions and can be counteracted by administration of the relevant coagulation factors. Rational hemotherapy aims at minimizing these transfusion-related complications by restricting the indications for blood transfusion, blood component therapy, peroperative normovolaemic haemodilution, preoperative deposition of autologous blood and/or peroperative collection of blood and re-infusion. Employing rational hemotherapy, it becomes possible to reduce the need for transfusion by 20-90% and hence the morbidity and the mortality connected with blood transfusion.
Blood Substitutes↗