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Biomedical subjects

P I Rafailidis

Publications and source records attributed to P I Rafailidis.

4 recordsLinked to original sources
PubMed2006

Effectiveness and nephrotoxicity of colistin monotherapy vs. colistin-meropenem combination therapy for multidrug-resistant Gram-negative bacterial infections.

A retrospective cohort study evaluated the effectiveness and nephrotoxicity of intravenous colistin monotherapy vs. colistin-meropenem combination therapy for patients with multidrug-resistant Gram-negative bacterial infections. Fourteen patients received intravenous colistin monotherapy and 57 received colistin-meropenem. No significant differences were found concerning clinical response of the infection (12/14 (85.7%) vs. 39/57 (68.4%), p 0.32) and development of nephrotoxicity (0/14 (0%) vs. 4/57 (7%), p 0.58). A favourable association was revealed between survival and treatment with colistin monotherapy compared to colistin-meropenem (0/14 (0%) vs. 21/57 (36.8%) deaths, p 0.007), even after adjusting for the variables for which significant differences were found.

Acute Kidney Injury↗
PubMed2005

Association between Wegener's granulomatosis and increased antithyroid antibodies: report of two cases and review of the literature.

We report two patients with severe manifestations of Wegener's granulomatosis, who also had significantly increased antithyroid antibodies. Auto-immune reaction against various human tissue antigens probably explains the association between increased anti-neutrophil cytoplasmic and antithyroid antibodies. The clinicians should include thyroid function and antithyroid antibody tests in the laboratory work up of the patients with Wegener's granulomatosis.

Adult↗
PubMed2004

Recurrent omphalitis in adults.

Recurrent omphalitis is seen more frequently in children, but clinicians world-wide are occasionally challenged by cases of recurrent omphalitis in adults. Apart from folliculitis and infections associated with pilonidal cysts and piercing of the umbilical area, the clinician should consider the possibility of infected remnants of the allantois or the omphalomesenteric (vitelline) duct in adult patients with recurrent omphalitis. Imaging tests such as ultrasound and computed tomography scan frequently help to identify the exact cause of recurrent omphalitis. The combined surgical and medical management usually leads to cure of the problem.

Adult↗