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Biomedical subjects

P Itkonen

Publications and source records attributed to P Itkonen.

5 recordsLinked to original sources

Development of a regional health care network and the effect of knowledge intensive work on personnel and organisation.

OBJECTIVES: a) To present a regional health care communication system developed in the North Karelia Hospital District with the help of two EU funded information technology projects namely the TERVE project (1) which was implemented at the national level financed by the regional subsidy 6 of the ERDF and the CHIN project (2) that was implemented at the European level. b) To present the questions and issues that arose when implementing new technologies in a regional health care environment. RESULTS: Transformations in information technology are usually parts of other organisational transformations in health care. As a result of these issues, implementation of great information technology transformations has failed because of too strong a technology emphasis, insufficient participative touch and underestimation of social factors. Another result is that there is a cultural shock for physicians working in organisations where there are networks rather than hierarchies and relationships are predominantly contractual rather than professional. CONCLUSIONS: The effectiveness, productivity and profitability of the hospitals will be decisively dependent on information technology as well as its regional applications. Transformations in information technology are parts of other organisational transformations in health care, and can induce cultural shocks for physicians since the networked environment has a different philosophy than the hierarchy-based environment which was the case until recently. Finally, in a taxation based system, one key requirement is to understand that the network contacts and the time spent on networks must bring additional value to health care.

Decision Support Systems, Clinical↗

Information technology as tool for change.

It looks that networking welfare thinking and implementations of network projects only follow the development of data transfer possibilities. It is a danger that seamless chain of care in health care is just a data transferring generator based on easy connections, only creating needs for new data transferring. This is an 'illusion of core skills' that does not extend to the development of the contents of services. Easy access to the system makes more contacts and need for more also clinical services. New needs for data transfer burden the personnel with unnecessary information and networking functional model does not emancipate them to use their substantial skills. It means more costs and it is also a danger that normal life will be medicated. Public sector cannot finance all these new possibilities and consequences of modern technology. Does all this create a new combination of public and private sector and push them to allocate responsibilities in developing work? If the public and private sectors do not find the balance in controlling this development, also actors outside health care get to influence the choices and health care loses its autonomy. It becomes a business means for companies producing data transfer and network services. From the prioritization point of view this is not a good vision for financing and delivery of health care services either in public or private sector.

Finland↗

Mitochondrial flocculent densities in ischemia. Digestion experiments.

Flocculent densities appear in the mitochondrial matrix during ischemic damage. These densities were examined in kidneys after 2 hours of autolysis. The samples were embedded in water-miscible glycol methacrylate (GMA). Ultrathin sections on copper grids were digested with pronase, trypsin, ribonuclease T1, various phospholipases (A2, C, D), lipase, and desoxyribonuclease I. For statistical analysis the mean number (+/- SD) of densities per mitochondrion was determined in tubular epithelial cells. A statistically significant (p less than 0.001) decrease in the number of densities was apparent after treatment with pronase (75.5%) of the densities digested completely) and with trypsin (43.3% of the densities digested completely). Digestion with other enzymes did not significantly decrease the number of densities. This study provides quantitative support for the hypothesis that flocculent densities are composed of proteins, most probably mitochondrial membrane proteins or matrix proteins. The results do not support the hypothesis that RNA, neutral lipids, phospholipids or DNA are major constituents of these structures.

Animals↗