Biomedical subjects

P Iwens

Publications and source records attributed to P Iwens.

3 recordsLinked to original sources

PubMed1994

[Sinusitis in atopic children].

Allergy is one of the etiologic factors in the pathogenesis of sinusitis. In order to investigate the allergic influence on the incidence of sinusitis, a CT-scan of the sinuses in 59 atopic children with nasal complaints of rhinosinusitis was performed. Sinusitis was found in 36 children (61%). These results were compared to a previous study of 196 mainly non-atopic children (atopy was no exclusion criteria). Identical inclusion and evaluation criteria were used. Sinusitis was found in 125 children (64%). According to these results it seems that the prevalence and the extent of sinusitis is not determined by the presence of allergy.

Adolescent↗

PubMed1994

Sinusitis in allergic patients.

Allergy is one of the aetiologic factors in the pathogenesis of sinusitis. To determine its influence on the occurrence of sinusitis the authors studied CT-scans of the sinuses in 59 allergic children and 62 allergic adults. Sinusitis was found in 36 children (61%) and 36 adults (58%). These results were compared with two previous studies consisting of mainly non-allergic children (n = 196) and mainly non-allergic adults (n = 350). Except for allergy, identical inclusion and evaluation criteria were used. In the previous studies, sinusitis was found in 125 children (64%) and 201 adults (57.5%). According to these results it seems that the prevalence and the extent of sinus mucosa involvement is not determined by aetiology (allergic or non-allergic). Age seems to be of major importance regarding the extent of sinus disease.

Adult↗

PubMed1991

[Premalignant lesions of the laryngeal epithelium].

At the Academic Hospital of the Free University of Brussels 243 patients underwent microlaryngoscopy over a period of 11 years (1978-1989). Histologic examination disclosed premalignant lesions in 55 patients. 26 patients had a follow-up (mean follow-up time was 5 years) and were selected for this study. The patients with premalignant lesions were divided into 3 groups: group 1 = hyperplasia and/or keratosis with or without mild dysplasia (11 patients); group 2 = mild dysplasia (7 patients); group 3 = severe dysplasia and carcinoma in situ (8 patients). In group 1 no malignant transformation was seen. In group 2 one invasive carcinoma developed after a period of 5 years (14%) and in group 3 two malignant transformations appeared 14 and 15 months after the initial diagnosis (25%). The treatment of choice was a total excision biopsy or stripping. A life time follow-up with an interval period of 6 months is recommended. The patients were also motivated to change their smoking habits.

Adult↗