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Biomedical subjects

P J Blackburn

Publications and source records attributed to P J Blackburn.

4 recordsLinked to original sources
PubMed2001

Optic disk edema as a presentation of Propionibacterium acnes endophthalmitis.

PURPOSE: To report a patient with an initial presentation of optic disk edema secondary to Propionibacterium acnes endophthalmitis. METHODS: Interventional case report. The patient had surgery and treatment related to endophthalmitis. Nine months after cataract surgery with posterior chamber lens implant, a 79-year-old man receiving topical corticosteroids in the same eye presented with best-corrected visual acuity of 20/60, a superior visual field defect, and optic nerve edema without intraocular inflammation. One year postoperatively, the eye presented a further decrease in best-corrected visual acuity, and a dense white plaque was noted on the posterior capsule. RESULTS: One year postoperatively, a partial capsulectomy with vitrectomy and injection of intravitreal antibiotics was performed. Hematoxylin and eosin stain of the posterior capsule plaque revealed gram-positive coccobacilli characteristic of P. acnes. CONCLUSION: Propionibacterium acnes endophthalmitis may present after cataract surgery with intraocular lens implant with decreased vision, optic disk edema, and a visual field defect.

Aged↗
PubMed1984

Effect of repeated hyperbaric exposures on the menstrual cycle: preliminary study.

Two healthy female volunteers were subjected to hyperbaric air pressure of 5 ATA comparable to 130 feet of sea water (fsw) for 20 min 7 or 8 times during their menstrual cycles (experimental cycles). During the experimental cycles hormone assays for follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol, progesterone, and testosterone were performed before and after each dive on alternate days between the 5th and 11th cycle days (follicular phase), daily during the time ovulation was expected to occur, and on alternate days during the luteal phase; these were compared with the same assays throughout control cycles, during which the subjects were not pressurized. Periodic pressurization produced no significant changes in hormone patterns; ovulation was not inhibited and menstrual periods were unchanged.

Adolescent↗
PubMed1983

Hyperbaric exposure during pregnancy in sheep: staged and rapid decompression.

Hyperbaric exposure during pregnancy in sheep: staged and rapid decompression. Undersea Biomed Res 1983; 10(1): 11-15. --Twelve sheep with dated pregnancies were exposed for 20 min to hyperbaric pressure comparable to 165 feet of sea water weekly between the 49th and 133rd days of pregnancy. Six were decompressed in stages and six directly without decompression stops. Those that were decompressed gradually delivered normally at or near term. One lamb was abnormal, but the relationship to pressurization is unclear. Three of those decompressed rapidly aborted dead fetuses, and two others delivered mature, but affected, lambs. Under the conditions of this study staged decompression after repeated hyperbaric exposures protected the fetuses from the destructive effects of rapid decompression. Hyperbaric pressure did not alter gross anatomic development.

Abortion, Incomplete↗