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Biomedical subjects

P J Diaz

Publications and source records attributed to P J Diaz.

6 recordsLinked to original sources
PubMed1996

Dorsal midbrain syndrome due to mesencephalic hemorrhage. Case report with serial imaging.

Spontaneous, nontraumatic, nonhypertensive, midbrain hemorrhage is an uncommon cause of the dorsal midbrain syndrome. We describe a patient with this syndrome in whom the initial neuroimaging studies failed to clearly identify the lesion. Subsequent magnetic resonance imaging studies disclosed a dorsal midbrain hemorrhage. The patient experienced gradual spontaneous resolution of her dorsal midbrain signs and symptoms over several months. The evolution on serial neuroimaging studies of the dorsal midbrain hemorrhage in this patient is described.

Aged↗
PubMed1983

Intercalated discs as a cause for discontinuous propagation in cardiac muscle: a theoretical simulation.

A theoretical model of a cardiac muscle fiber (strand) based on core conductor principles and which includes a periodic intercalated disc structure has been developed. The model allows for examination of the mechanism of electrical propagation in cardiac muscle on a microscopic cell-to-cell level. The results of the model simulations demonstrate the discontinuous nature of electrical propagation in cardiac muscle and the inability of classical continuous cable theory to adequately describe propagation phenomena in cardiac muscle.

Action Potentials↗
PubMedDate not supplied

MR susceptometry: an external-phantom method for measuring bulk susceptibility from field-echo phase reconstruction maps.

A novel method for estimating the susceptibility of an object by using the magnetic resonance (MR) imaging field distortions in an external-reference water bath next to the object is described. The field measurement was obtained with a phase reconstruction from a gradient-echo acquisition. A field model of an arbitrary object in a static magnetic field was discretely calculated from geometry determined from the magnitude reconstruction. Least-squares estimation yields the susceptibility of the object. Required (and proven) assumptions include validity of superposition, object homogeneity, negligible higher-order field terms, field-model accuracy, geometric-model accuracy, and correlation of gradient-echo phase to field distortion. MR susceptometry estimation of phantoms yielded susceptibility estimates that correlated well with known values (r > .9975). This MR susceptometry method is a first step toward quantitation of iron levels through MR imaging phase information in patients with iron overload.

Algorithms↗
PubMedDate not supplied

MR of ballistic materials: imaging artifacts and potential hazards.

The most common ballistic materials available in the urban setting were studied for their MR effects on deflection force, rotation, heating, and imaging artifacts at 1.5 T to determine the potential efficacy and safety for imaging patients with ballistic injuries. The 28 missiles tested covered the range of bullet types and materials suggested by the Cleveland Police Department. The deflection force was measured by the New method. Rotation was evaluated 30 min after bullets had been placed in a 10% (weight per weight) ballistic gelatin designed to simulate brain tissue, with the long axis of the bullet placed parallel and perpendicular to the Z axis of the magnet. Heating was measured with alcohol thermometers by imaging for 1 hr alternatively with gradient-echo and spin-echo sequences (RF absorption = 0.033 and 0.326 w/kg respectively). Image artifacts on routine sequences were evaluated. All the steel-containing bullets except for the Winchester armor-piercing 38 caliber exhibited deflection. A nonsteel 7.38-mm Mauser also deflected. Deflection range was 514 to 15,504 dynes. Rotation occurred when the bullets were not parallel to the Z axis. Temperature changes were not significant. Deflecting projectiles resulted in obliteration of the image. The artifacts from other projectiles were small but varied by content. The artifact of the Winchester armor-piercing 38-caliber bullet was similar to those without steel. Bullets that contain steel or ferromagnetic contaminates such as nickel can be rotated within the MR unit.(ABSTRACT TRUNCATED AT 250 WORDS)

Firearms↗