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P J Doyle

Publications and source records attributed to P J Doyle.

At least 37 records · Page 2Linked to original sources

Experimental analysis of syntax training in Broca's aphasia: a generalization and social validation study.

A multiple baseline design across responses was used to examine the effect of syntax training on the sentence production of 4 individuals with chronic Broca's aphasia. Subjects were trained to produce five exemplars of five sentence types from Helm's Elicited Language Program for Syntax Stimulation (Helm-Estabrooks, 1981). Generalization and maintenance of trained sentence types to novel exemplars and novel stimulus conditions served as dependent measures. In addition, five naïve judges rated subjects' responses before and following the treatment in terms of their "adequacy." Generalization to novel exemplars was demonstrated sequentially by 3 subjects (i.e., following the teaching of all five forms), and the remaining subject demonstrated generalization for three of five sentence types trained. Maintenance was variable across subjects and sentence types. Generalization across stimulus conditions was limited for all subjects. Adequacy judgments revealed improved communication skills for wh-questions but limited changes in the perceived adequacy of subjects' declarative responses. These findings indicate that the effects of syntax training procedures are limited to those grammatical constructions taught, that generalization of learned forms to novel stimulus conditions is not an automatic consequence of acquisition, and that the effect of such training on the adequacy of subjects' responses may be limited.

Adult↗

Management of tinnitus: a practical approach.

This paper presents our experience with 500 patients with intractable tinnitus who were referred to our tinnitus clinic during the past 10 years. We propose a management plan based on identification and classification of three types of tinnitus. We describe what a tinnitus clinic adds to patient care, with emphasis on how these treatment methods can be utilized in office practice.

Adult↗

Cancer of the tonsil.

One hundred and twenty-two patients with cancer of the tonsil presented at the University of British Columbia Cancer Control Agency between 1970-80. The results of treatment are reviewed. Eight-six patients (70.5%) were treated with radiotherapy alone. The overall three year corrected survival rate is 54.4% and the five year corrected survival rate is 45.6%. Local control varied from 86% (T1 lesions) to 47.5% (T3 lesions). Nodal disease was present in 65%. Recurrences developed in 55.8% of the patients. Salvage surgery was performed in 15 patients with a success rate of 39%. When compared to a study in 1977, results are improved. We feel that this was due to more standardized treatment, improved salvage surgery, and improved radiation therapy. Findings in this study indicate that primary radiotherapy with salvage surgery is a satisfactory treatment approach for patients with cancer of the tonsil.

Adult↗

Subcutaneous mastectomy for primary operable breast cancer.

Subcutaneous mastectomy has been performed on 98 patients with primary breast cancer. Eighty-four have undergone breast reconstruction using a silicone prosthesis. The overall complication rate has been low. The rates of local recurrence and survival are similar to those in patients undergoing simple mastectomy.

Breast↗

Paranasal sinus malignancy--a retrospective analysis of treatment methods.

A retrospective analysis has been made of all cancers of paranasal sinuses seen at the Cancer Control Agency in Vancouver during the years 1970 to 1978. The overall crude five year survival for all cases (49) was 46%. A combined treatment using irradiation and surgery in selected cases generated a five year survival rate of 74.4% as compared to 42.1% in cases receiving irradiation alone. The clinical presentation, staging, and the need for the individualization of treatment methods based on a realistic knowledge of the pathological extent of the disease are discussed.

Adenocarcinoma↗

The tuning fork--an essential instrument in otologic practice.

Two groups of people are critical of the tuning fork--those who have never used them and those who do not know how to use them. The tuning fork correctly used is still a dependable method of diagnosing conductive hearing loss and invaluable in the diagnosis of unilateral total sensorineural hearing loss. The degree of conductive loss can be estimated by using tuning forks of 256 through 1024 frequency. These statements are based on the results of this study in which tuning fork tests were performed on a series of patients who subsequently underwent complete otologic examination and audiometry. The method of tuning fork use, the value particularly in the diagnosis of conductive hearing loss, and the tuning fork's limitations are discussed.

Audiometry↗

Initial results from a programme of breast self-examination.

As part of a national study of early detection of breast cancer, 28663 women aged between 45 and 64 have been invited to attend a teaching programme on the method of self-examination with the advice to practise it regularly. This paper reports the early results of the Nottingham study on 14905 who have attended. To date there have been 717 self-referrals. One hundred and thirty-nine of these had a significant abnormality on either clinical examination or mammography and eight biopsies have been performed. Cancer was detected in 43 women. This is a detection rate of 2.9 cancers per 1000 educated. Mean tumour size was 2.3 cm (0.5-6.0 cm) and 56% were lymph node negative.

Biopsy↗

The value of routine peroperative cholangiography--a report of 4000 cholecystectomies.

A total of 4000 consecutive cholecystectomies performed over a period of 25 years has been analysed to determine whether routine peroperative cholangiography (PC) has influenced overall mortality. The patients have been divided into four cohorts of 1000, the first cohort before the introduction of PC, two covering the period of introduction of PC and the final cohort when PC was an established routine. A significant fall in overall mortality has been demonstrated, but when the patients are divided into simple cholecystectomy and the group undergoing additional choledochotomy there is no significant fall in the mortality rate. The mortality rate for the latter group is three or four times greater than that for the cholecystectomy alone group. The main contribution to the lower mortality is the reduced duct exploration rate following the introduction of PC. The stone recovery rate has improved from 34 to 71 per cent. The use of routine PC during cholecystectomy is recommended.

Cholangiography↗

A prognostic index in primary breast cancer.

From a multiple-regression analysis of prognostic factors and survival in a series of 387 patients with primary breast cancer, a prognostic index has been constructed, based on lymph-node stage, tumour size and pathological grade. This index is more discriminating than lymph-node stage alone, and enables a larger group of patients to be identified with a very poor prognosis.

Adult↗

Choice of treatment for chronic suppurative otitis media.

Many otolaryngologists appear to be confused regarding the indications for tympanoplasty and the choice of procedure for tympanoplasty, particularly if there is associated mastoid disease. This paper presents one otolaryngologist's approach to the patient with chronic suppurative otitis media and describes the indications for surgery and choice of surgical procedure based on a simple classification of the disease process.

Cholesteatoma↗

Experiences with the homograft tympanic membrane.

Forty-three patients who underwent tympanoplasty with the use of a homograft tympanic membrane are reviewed. These procedures were performed by 10 different surgeons over a period of six years. The success rate of tympanic membrane closure, hearing results, and incidence of complication were studied. Results were examined to determine possible factors contributing to failure. The success rate and lack of complications suggest that homograft tympanic membrane tympanoplasty is a useful procedure, particularly where the blood supply to the tympanic remnant is felt to be in jeopardy.

Hearing↗

Relationship between primary breast tumor receptor status and patient survival.

For a minimum of 3- months, 250 women who underwent mastectomy for primary breast cancer have been followed up. ER status has had a pronounced effect upon disease-free interval and survival: in patients with node involvement ER-positive (ER+) tumors carry a better prognosis. Of patients with ER-positive primary tumors, 43% underwent objective response to their secondaries for a minimum period of six months. This compares with a response of only 18% for ER-negative (ER-) tumors. In patients who had previously received endocrine therapy and on relapse were treated with cytotoxic chemotherapy, objective response rate to chemotherapy was better in patients in whom the primary tumor had been ER-, but not significantly so.

Adult↗