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Biomedical subjects

P J Early

Publications and source records attributed to P J Early.

5 recordsLinked to original sources
PubMed1995

Use of diagnostic radionuclides in medicine.

The purpose of this paper is to follow the course of historical development in the use of radiopharmaceuticals as a diagnostic tool in nuclear medicine. This course has been a series of plateaus and growth spurts throughout its history. This article is designed to identify the different phases of the development of nuclear medicine, pointing out the events which most shaped its history along the way. Those events included such things as the discovery of radioactivity, the development of the cyclotron and nuclear reactor as a method of producing high specific activity radioactive material, the development of imaging equipment such as the rectilinear scanner, scintillation camera, PET and SPECT, the application of computers, and the discovery of 99mTc and the development of associated kits designed to image many organs and processes in the human body.

History, 20th Century↗
PubMed1995

Use of therapeutic radionuclides in medicine.

The purpose of this paper is to follow the course of historical development in the use of radiopharmaceuticals as a therapeutic tool in nuclear medicine. This chapter is designed to point out the different phases of the development of therapeutic nuclear medicine, pointing out the events which most shaped its history along the way. Those events included the discovery of radioactivity, the development of the cyclotron and nuclear reactor as a method of delivering high specific activity radioactive sources, and a few significant therapeutic radionuclides such as 131I and 32P. The most significant therapeutic radionuclide was radium, which is treated very extensively in this paper from an historical viewpoint. It is only recently that attention of the nuclear medicine community turned to new therapeutic agents, such as bone pain palliation agents, monoclonal antibodies, and others. It may be that the next growth phase of nuclear medicine will revolve around therapy with these radionuclides.

Brachytherapy↗
PubMed1987

Radiation safety and handling of therapeutic radionuclides.

The use of radionuclides in therapy, both as sealed sources and in the radiopharmaceutical form, is discussed from receipt of radiopharmaceuticals through their use, to their disposal. The licensing requirements for use of therapeutic radionuclides is presented. Discussions dealing with receipt, storage and administration of radiopharmaceuticals are treated in detail, as well as suggestions for personnel monitoring. Procedures involved in the event of emergency surgery and/or death are discussed. The misadministration rules of the Nuclear Regulatory Commission regarding therapies were presented.

Accident Prevention↗