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P J Fournier

Publications and source records attributed to P J Fournier.

6 recordsLinked to original sources
PubMed1996

Evaluation of the clinical safety and efficacy of iobitridol (Xenetix) in intravenous urography.

The aim of this study is to report on the clinical safety and diagnostic efficacy of iobitridol (Xenetix) in intravenous urography compared to iohexol (Omnipaque) or iopamidol (Iopamiro). A total of 120 patients underwent intravenous urography (i.v.u.); 60 received Xenetix and 60 either Omnipaque (30 patients) or Iopamiro (30 patients) according to the center where they were treated. Clinical safety was assessed by the reporting of adverse events and diagnostic efficacy was evaluated. Warmth sensation was the most commonly reported adverse event. Two cases of nausea and vomiting were reported. Concerning diagnostic efficacy, 72-74% of the i.v.u. examinations were rated good or excellent by the physician. These studies confirm that Xenetix is a suitable contrast agent for i.v.u.

Contrast Media↗
PubMed1995

[A comparative study of the imaging quality and picture dosage of a new conventional film-screen system for skeletal x-ray diagnosis].

PURPOSE: This paper compares a new film-screen system (FSS) called INSIGHT Skeletal Imaging System with the previously used Lanex/T-MAT G FSS. MATERIAL AND METHODS: Using a Bronder phantom, measurements were made of dose, resolution and contrast. 135 skeletal phantom images were assessed in order of quality by six observers. RESULTS: Comparable high resolution film-screen combinations (FSC) showed similar geometric resolution. Comparing high intensifying screens, the new INSIGHT Skeletal Regular FSS showed better resolution than the Lanex medium FSC. Dose reduction for the INSIGHT Skeletal Imaging FSS was 29-56%. The new FSS showed image quality similar to high resolution screens but was significantly better when using high intensifying screens. CONCLUSION: The new INSIGHT Skeletal Imaging System can replace the Lanex/T-MAT G FFS by retaining quality but reducing radiation dose by 29-56%. Using the new high intensifying FSC, images showed in addition improved film quality.

Bone and Bones↗
PubMed1985

Chorionic villi sampling: clinical experience, immediate complications, and patient attitudes.

To develop chorionic villi sampling as a procedure for prenatal diagnosis, a pilot study was undertaken to perfect the obstetric and laboratory techniques, to evaluate our success with the procedure in continuing pregnancies, and to assess the attitudes of potential users of the procedure. Women about to have elective first-trimester abortions for nongenetic reasons were enrolled in the first phase of the study. Of the patients with a positive pregnancy test, 12.4% were found to have a nonviable pregnancy on ultrasound examination. Samples adequate for cytogenetic analysis were obtained in 130 of the 155 remaining cases, and the success rate was 93% in the 100 most recent cases. Direct cytogenetic analysis was undertaken in those cases successfully sampled, and karyotypes could be prepared in 97%. Immediate complications occurred in 5% of the pregnancies. Eight women at risk of bearing a child with a genetic defect had diagnostic chorionic villi sampling. Cytogenetic analysis was performed successfully on all of them. One had an induced abortion following the procedure because of the fetal diagnosis (a male with a 50% risk of Duchenne's muscular dystrophy). The other pregnancies are continuing uneventfully at 22 to 35 weeks' gestation. Finally, from preliminary analysis of our survey of potential users it appears that women 35 years old or over would prefer chorionic villi sampling to amniocentesis if the risks of the sampling were known to be low.

Adult↗