PubMed Health⌕ Search

Biomedical subjects

P J Hooft

Publications and source records attributed to P J Hooft.

7 recordsLinked to original sources
PubMed1997

Bayesian evaluation of the modified zinc test and the acid phosphatase spot test for forensic semen investigation.

The modified zinc test is evaluated as a screening instrument in forensic semen identification using the classical acid phosphatase test as a "gold standard" reference. Both tests were applied to vaginal swabs taken from women (n = 456) at varying time periods after sexual intercourse and the corresponding sensitivity and specificity were calculated for both tests separately and for their parallel and serial combination strategies, with the microscopical visualization of sperm as end criterion. The results were submitted to Bayesian calculations and a model was obtained, giving the posterior probabilities of finding or not finding sperm in a microscopical preparate for any possible prior probability. For the largest part of the theoretical sperm prevalence range, negative predictions were more informative than positive ones. With the prior probability of finding spermatozoa set at P = 0.5 (Bayes' postulate of neutral prior probability), the model was applied to a set of 192 pieces of evidentiary material from alleged sexual assaults.

Acid Phosphatase↗
PubMed1995

[Predictive value of anthropometric parameters for birth weight].

A random series of 1,000 parturients in 2 maternity wards in Kinshasa in 1992 were studied. Several parameters affecting birthweight were measured. The predictive value of the Quetelet index, determined by Spearman correlation, was greater than the predictive value of skin folds, brachial circumference, adipose and muscular surfaces or fat mass and was slightly better than lean mass. Anthropometric measurements have certain inconvenience and other factors affect birthweight. These results suggest that the Quetelet index is a sufficiently precise tool for evaluating nutritional state. In addition, its use would allow more time for patient counselling. The longer doctor-patient dialogue could have an effect on prevention in the area of psycho-social stress. This latter factor, combined with the cumulated stress score, was found to be one of the 3 main factors in multiple linear regression evaluation of birthweights reported here.

Birth Weight↗
PubMed1994

Interference of body products, food and products from daily life with the modified zinc test and the acid phosphatase test.

The modified qualitative zinc test and the qualitative acid phosphatase test were applied to a total of 1774 semen-free stains made from human body products (n = 575), food products (n = 801), beverages (n = 146), water (n = 120) and other products from daily life (n = 132), in order to assess the degree of interference of these products with the preliminary screening for semen. The zinc test gave positive results in, respectively, 2.4, 3.1, 1.4, 14.1 and 23.5% of the samples, whereas the acid phosphatase test was positive in 3, 3.3, 0, 1.7 and 0% of the samples. Given the large number of positive test results found for products which eventually may be present in stains from alleged sexual assaults, it is concluded that positive screening test results should be interpreted with great caution.

Acid Phosphatase↗
PubMed1994

Reckless behaviour related to the use of 3,4-methylenedioxymethamphetamine (ecstasy): apropos of a fatal accident during car-surfing.

A 26-year-old man died from severe brain contusion after falling from a moving car during an attempt at car-surfing. Toxicological urine screening was positive for amphetamines, the blood analysis revealed a MDMA level of 0.63 mg/l and a blood alcohol concentration of 1.23 g/l. The case is another example of the bizarre and reckless behaviour which may result from the euphorogenic activity of ecstasy and the circumstances in which it is commonly used.

Accidents, Traffic↗
PubMed1990

The zinc test as an alternative for acid phosphatase spot tests in the primary identification of seminal traces.

The value of the acid phosphatase spot test in the primary visualization and identification of seminal traces is hampered by the sensitiveness of the enzyme to biodegradation. An alternative spot test is proposed, based on the high concentration of the more stable zinc metal in seminal plasma. The proposed zinc spot test is simple and suitable for on site investigation. Although the sensitivity in fresh stains is lower than that of the acid phosphatase spot test, this is largely compensated by the lower sensitiveness to biodegradation. The specificity for semen is higher than that of the acid phosphatase spot test. In vaginal swabs it was nevertheless seen, that samples should be taken within 24 h after alleged sexual assault to give reliable results.

Acid Phosphatase↗
PubMed1989

Fatality management in mass casualty incidents.

Medical involvement in mass casualty incidents requires proper planning and preparedness. In disaster situations, legal aspects concerning the dead add to the general problem of a lack of time, place and resources to maintain routine working conditions, and demand authority and competence. The aspects of planning the recovery of the dead, transportation and morgue facilities, establishment of cause of death, identification, and the final disposition of the dead are discussed. The implementation of forensic mass fatality teams is felt to be the right answer for a better planning and coordination.

Autopsy↗