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Biomedical subjects

P J Lipsitz

Publications and source records attributed to P J Lipsitz.

6 recordsLinked to original sources
PubMed1979

Congenital unilateral ichthyosis in a newborn.

Ichthyosiform erythroderma is a rare phenomenon occurring in about 1/300,000 live births. Congenital unilateral ichthyosis, described in this case report, is a clinical variant of ichthyosis. Only five previous cases have been reported. In the patient described in this report, superimposed infection of the affected skin developed. Her immunologic system was intact. She manifested failure to thrive, in spite of an adequate caloric intake, and markedly delayed psychomotor development. This patient also demonstrated absorption from the affected dermis of topically applied urea hydrophilic base ointment. She died before her first birthday.

Female↗
PubMed1979

Lipoprotein-X and other tests in the diagnosis of obstructive jaundice in the infant.

The infant with elevated direct-reacting bilirubin levels requires an early specific diagnosis to identify those who would require early surgical intervention and those in whom the bilirubin levels will eventually return to normal. This study compares the accuracy of three tests: the serum lipoprotein-X (LP-X), the I131 rose bengal (IRB) excretion and the serum alpha-fetoprotein (AFP) in making a specific diagnosis in 15 patients. When used individually the accuracy of the tests varies from 56-100%. The LP-X and IRB excretion are more specific and when in agreement are 100% acurate in the diagnosis of the neonatal hepatitis syndrome (NHS) or extrahepatic biliary obstruction (EHBO). This study suggests that both the LP-X and IRB excretion should be used in the investigation of the infant with conjugated hyperbilirubinemia.

Biliary Tract Diseases↗
PubMed1977

Chylothorax in two mongoloid infants.

Two newborns with stigmata of Down syndrome required resuscitation at birth because of unilateral congenital chylous pleural effusion. After thoracentesis, ventilation was improved. Congenital chylous pleural effusion in newborns with Down syndrome has not previously been described. Pleural effusion at birth must be promptly diagnosed and aspirated.

Chylothorax↗