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P J LoPresti

Publications and source records attributed to P J LoPresti.

4 recordsLinked to original sources

Case report: severe microcytosis associated with the anemia of chronic disease.

When microcytosis is present in patients with anemia of chronic disease, the mean corpuscular volume (MCV) rarely if ever falls below 70 fL. The lowest MCV previously reported is 67 fL. We describe a patient with anemia of chronic disease with severe microcytosis and an MCV of 61 fL. After correction of the chronic disorder, complete correction of the hematologic values occurred. In patients with a low total iron binding capacity, iron therapy should not be instituted without clearly establishing the presence of iron deficiency irrespective of the degree of microcytosis.

Anemia↗

Acne vulgaris aggravated by sunlight.

The symptoms of approximately 3 percent of our patients with acne vulgaris worsen during the summer months even though they maintain previously effective therapy. We show herein that the addition of 5 percent para-aminobenzoic acid (PABA) in alcohol (used as a sunscreen) resulted in marked improvement in their ability to tolerate sunlight. This condition, acne vulgaris aggravated by sunlight, has been compared to acne aestivalis which is another sunlight-induced disorder.

Acne Vulgaris↗

Zirconium granuloma following treatment of rhus dermatitis.

Zirconium granuloma of the skin, initially seen following the use of zirconium deodorants, continues to occur secondary to the treatment of plant dermatitis with compounds containing zirconium. In our patient the reaction appeared eight weeks after initial use of the agent and has persisted for 18 months without therapy. Intradermal injection of minute amounts of a soluble zirconium compound resulted in production of a lesion that was identical clinically and histologically with the primary lesion at the end of four weeks. Although this disorder involves the skin primarily, the slight elevation in gamma-globulin level observed may be a reflection of its systemic pathogenesis.

Adolescent↗