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Biomedical subjects

P J Pinsent

Publications and source records attributed to P J Pinsent.

12 recordsLinked to original sources

An evaluation of the accuracy of ageing horses by their dentition: a matter of experience?

There is a widely held belief that a horse can be accurately aged by an examination of its teeth but this belief has recently been questioned. In this study photographs were taken of the dentition of 434 thoroughbreds of known age. Four experienced equine clinicians provided estimates of the ages of the horses from the photographs. A comparison of the estimated and true ages showed large discrepancies in many cases and the discrepancies increased as the horse's true age increased. The results show that the ageing of horses from their dentition is an imprecise science. It is suggested that written records of the dental features are made on each occasion when a dental examination is made and that veterinary surgeons advise clients that estimating a horse's age from dental criteria can provide no more than an 'informed guess'.

Age Determination by Teeth↗

Fever of unknown origin in the horse: a review of 63 cases.

Fever of unknown origin (FUO) is a syndrome characterised by prolonged, unexplained fever associated with non-specific signs of illness such as lethargy, inappetence and weight loss. This paper reviews the details of 63 horses affected by FUO. The cause was found to be infection in 43 per cent of the cases, neoplasia in 22 per cent, immune-mediated diseases in 6.5 per cent and miscellaneous diseases in 19 per cent; the cause remained undiagnosed in 9.5 per cent.

Animals↗

A progressive, familial myopathy of the pietrain pig: the clinical syndrome.

A familial progressive muscular weakness is described in a herd of pietrain pigs. The onset of disease was at two to three weeks of age taking the form of a muscular tremor when the piglets were standing. An impaired gait followed and by 12 weeks of age the pigs had become permanently recumbent. The observed incidence of the syndrome and the breeding data available were consistent with an autosomal recessive inheritance of the condition.

Animals↗

Optic neuropathy in a horse.

A 10-month-old thoroughbred colt developed sudden complete blindness; no other neurological abnormality was detected. At necropsy 3.5 months later lesions were confined to both optic pathways in which there was extensive degeneration of axons and myelin and gliosis. The cause of the optic lesion was not determined but the lesion may be a toxic neuropathy.

Animals↗

Intestinal obstruction in cattle.

Based on a series of 100 cases, the paper reviews the causes, diagnosis and treatment of apparent bowel obstruction in cattle with particular emphasis on non-obstructive tympanitic disorders of the intestine.

Acidosis↗

Rupture of the diaphragm in the horse.

Four cases of fatal diaphragmatic rupture in the horse are described. In 2 cases there was no history of injury but the other 2 animals had sustained recent thoracic trauma. Three of the horses had signs of colic and bowel obstruction complicated, in 2 cases, by respiratory embarrassment; the fourth died rapidly, presumably of shock. Previously published cases are reviewed and the causes, clinical effects, diagnosis and treatment of the disorder are discussed.

Animals↗

The indications for equine laparotomy--an analysis of 140 cases.

The indications for laparotomy in 140 horses are analysed, with particular emphasis on the operative or autopsy findings in 82 cases of colic. In cases of exploratory laparotomy, the overall recovery rate was only 28 per cent but 48 of the 82 animals were considered to have inoperable lesions. The recovery rate and causes of death for each indication are briefly reviewed.

Animals↗

Malabsorption in the horse associated with alimentary lymphosarcoma.

Three horses suffering from malabsorption were shown to have alimentary lymphosarcoma predominantly affecting the small intestine and the associated lymph nodes. The diffuse cellular infiltration in two of the case produced marked changes in the villous architecture reducing the available mucosal surface area, and, with lowered or barely detectable disaccharidase activities, contributed to the impairment of digestive-absorptive processes. One of the horses maintained a voracious appetite and was not diarrhoeic, but failed to gain weight, indicating differences in the production and utilisation of energy sources absorbed from the small and the large intestines. A large proportion of plasma cells in the infiltrate, and the resulting morphological changes in two of the cases bore a striking resemblance to features of alpha chain disease, an immunodeficiency disease of man, although immunological studies were not conducted on these horses.

Animals↗