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Biomedical subjects

P J Stephen

Publications and source records attributed to P J Stephen.

7 recordsLinked to original sources

A study of zinc status of elderly institutionalized patients.

In a study of zinc status in the elderly, the mean serum and leucocyte zinc concentrations were found to be significantly lower in continuing-care patients compared with elderly people living in the community. The mean daily dietary intakes of zinc, protein and fibre did not differ between the two groups. Serum zinc levels were found to correlate with serum albumin levels. No significant relationship was found between the mean serum or leucocyte zinc concentrations of patients and either their mental status or the presence of skin pressure damage, leg ulcers or unhealed wounds.

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Career patterns of women medical graduates 1974-84.

A postal questionnaire was carried out in 1984 to determine the career pattern of United Kingdom women medical graduates of 1974. The response rate was 57%. The median age was 33 and 82% were married. Eighty-nine per cent were employed in a vast range of specialties; most of those not working at the time of the survey planned to return to work within 6 months. Many expressed a need for more career advice at all stages, and for more training in the community-based specialties.

Adult↗

Drug-induced parkinsonism in the elderly.

Of 95 new cases of parkinsonism referred to a department of geriatric medicine, 48 (51%) were associated with prescribed drugs. Clinical features in drug-induced and idiopathic cases were very similar, including the proportion with typical tremor. 25% of patients with drug-induced parkinsonism (DIP) could not walk when first seen and 45% required hospital admission (for a median stay of 23 days, range 5-101). The clinical features of DIP resolved permanently in two-thirds of cases in a mean of 7 weeks but with a range of 1 to 36 weeks. 5 cases of DIP initially resolved but idiopathic parkinsonism developed after an interval of 3 to 18 months. Perhaps some old people have low striatal dopamine levels and a small neuroleptic effect tips them into overt parkinsonism or unmasks latent idiopathic disease. The commonest offending drug was prochlorperazine (21 cases). In no case did this drug seem to be indicated.

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