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Biomedical subjects

P Jardel

Publications and source records attributed to P Jardel.

14 recordsLinked to original sources

[Fatal mesenteric ischemic accident caused by mesenteric inflammatory veno-occlusive disease].

A 72-year-old woman in good general health presented a massive intestinal and colonic ischemia with rapid post-operative death, due to mesenteric inflammatory veno-occlusive disease. Mesenteric inflammatory veno-occlusive disease, first described in 1994, is a vasculitis of unknown etiology limited to the mesenteric area, affecting exclusively veins and venules and sparing arteries. Histologically, there are acute lesions of lymphocytic and/or necrotizing, sometimes granulomatous phlebitis and chronic lesions of myointimal hyperplasia reducing the lumen of the veins. In this case, polymorphonuclear eosinophils were particularly numerous.

Aged↗

[Rectal linitis plastica with urologic presentation. Apropos of 3 cases].

The authors report three cases of rectal linitis plastica which presented in a novel manner by urological manifestations. The diagnosis of these lesions was based essentially upon deep rectal, bladder and prostate biopsies as well as CT scan. These three clinical cases illustrate the dreadful prognosis of rectal linitis plastica, agreeing with conclusions emerging from a review of the literature.

Adenocarcinoma↗

[Treatment of major eventrations. Original use of polyglactin 910 plaques].

An original procedure for treating major incisional hernias is described. A polyglactin 910 plate is hemmed around the edges of the hernia, then tightened by degrees with wide separate stitches until these edges are closely approximated on the midline under low tension, all the forces being distributed over the whole surface of the plate. This procedure can be used alone or associated with another procedure.

Hernia, Ventral↗

[Primary cancers of the gallbladder. Apropos of a homogeneous series of 75 cases].

Seventy-five cases of primary carcinoma of the gallbladder are reviewed retrospectively under observation of a fifteen year period, representing 2.4 per cent of the number of biliary tract surgery performed during the same period. The majority of the patients presented with advanced disease with extension and metastases to the liver (56%) and to the adjacent organs (53.3%) and to the lymph nodes along the common bile duct (21.3%). Eleven patients had localized disease at the time of the operation; they were treated with cholecystectomy. Eight patients had clinically inapparent carcinoma at the time of the cholecystectomy; the diagnosis being established post-operatively by histologic examination of the excised gallbladder. There were no five years survivors in this second group of patients, but five of them are one year survival (62.5%) and one is still alive three years and six months after surgery. The remaining patients with inapparent carcinoma died within three years of the time of the operation. The present report emphasize the poor prognosis associated with carcinoma of the gallbladder and the presence of gallstones. Carcinoma of the gallbladder in our experience has proved curable only when accidentally discovered at cholecystectomy for presumed benign biliary tract disease. This fact plus the frequent and serious non neoplastic complications of neglected gallstones are strong indications for early elective cholecystectomy and extended resection may improve the survival rate.

Adult↗

[Generalized peritonitis of non-traumatic colonic origin. Reflexions on 62 cases].

The authors analyze sixty-two cases of acute generalized peritonitis with a non-traumatic colonic etiology. They point out that the prognosis depends on three main factors: the age of the patient, the time spent in diagnosis and the therapeutic difficulties. They recommend a gastrographin colonic enema to obtain earlier diagnosis, in the absence of radiological evidence of pneumoperitoneum, in elderly patients presenting with abdominal signs. They also recommend multistage surgical management combining effective drainage of the abdominal cavity with resection of the perforated segment of the colon, whenever there is extensive damage to the colon, or in the presence of a tumor. In their view, conservative surgery should be confined to strictly selected cases not involving tissue resection. These indications are essential if a satisfactory result is to be achieved.

Adult↗

[Pancreatitis: a little-known cause of ureteral obstruction].

Left ureteral stenosis induced by pancreatitis was observed in one case. Five similar cases have been reported in the literature. Ureteral obstructions may be found in two clinical contexts--patent pancreatitis or retroperitoneal fibrosis. The ureter may be simply compressed mechanically, or there may also be enzymatic or ischemic necrosis. The clinical approach should be directed towards treating primarily the pancreatitis and secondarily the urological pathology. As regards the urological treatment, ureterolysis or ilio-ureteroplasty are indicated in cases of organized irreversible ureteral stenosis.

Adult↗

[Abdominal aortic aneurysm detected by a consumption coagulopathy].

Consumption coagulopathy with clinical symptoms reveals aortic arterial aneurysm in less than 5%. Aneurysmal repair with graft is able to remove hemostasis abnormalities for a long time. The physiopathology of these abnormalities is described here through the study of an operated case. It is questionable to use heparinotherapy as exclusive treatment for non operated patients. Heparinotherapy during perioperative period is also a matter of debate. Surgical implications of the consumption coagulopathy are listed: preoperative plasma and platelets transfusions, fibrinogen and antithrombin III perfusions, meticulous hemostasis, minor dissection, use of a women graft. Coagulation disorders disappear before the first postoperative week. Persistent or recurrent consumption coagulopathy invite us to look for a pathological association which often turns out to be a neoplasm.

Aged↗