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Biomedical subjects

P Joensen

Publications and source records attributed to P Joensen.

14 recordsLinked to original sources
PubMed1997

High prevalence of Parkinson's disease in the Faroe Islands.

We used several case-findings methods and strict criteria for case ascertainment to diagnose parkinsonism and idiopathic Parkinson's disease (PD) in the Faroe Islands. In the last few years before the prevalence date of July 1, 1995, we searched various registries from pharmacies, hospitals, and general practices, and found 195 patients with suspected parkinsonism out of 43,709 inhabitants. After excluding those who died before the prevalence date or were treated with levodopa (LD) for other diseases, a total of 124 patients remained for study, of whom 122 participated. We found 102 patients with parkinsonism and 82 with PD versus the expected 53 (p < 0.001, age-specific prevalences in the county of Rogaland, Norway). The overall prevalence of PD was estimated to be 187.6 and the age-adjusted prevalence to be 183.3 versus 110.9 per 100,000 inhabitants in the county of Rogaland. Compared to the study from Rogaland, the mean age at onset of PD symptoms, the mean age at the prevalence date, and the duration of PD indicated that the higher prevalence was not due to either an early onset nor to a longer duration of PD. A lower proportion of definite PD, a lower mean score on the Hoehn-Yahr scale, and a lower average dose of LD suggest that the high prevalence may be due to early diagnosis and a higher ascertainment of cases with mild disease. However, a high incidence cannot be excluded.

Adult↗
PubMed1988

Danish very-low-dose aspirin after carotid endarterectomy trial.

The effect of very-low-dose aspirin as an antithrombotic agent was evaluated blindly in 301 patients who had recently undergone carotid endarterectomy. After randomization, 150 patients received aspirin and 151 received placebo. The two groups were comparable with regard to age, sex, blood pressure, previous cerebrovascular events, and smoking habits. The effect of the study medication on platelet aggregation was measured twice in each patient during the first 2 months and at each follow-up visit; the dose was individually adjusted. In 76% of the patients receiving aspirin, 50 mg/day gave satisfactory platelet inhibition, 13% needed 60 mg/day, 8% needed 70 mg/day, and 3% needed 100 mg/day. Platelet aggregation was found to be inhibited in only 1.2% of the measurements in the patients receiving placebo. Observation during treatment averaged 21 months; total intention-to-treat follow-up averaged 25 months. For the combined outcome events of transient ischemic attack, stroke, acute myocardial infarction, and vascular death, aspirin reduced risk by 11% (95% confidence limits: -38% to 48%, p greater than 0.1). Thus, there was no significant effect of very-low-dose aspirin in our trial.

Aspirin↗
PubMed1986

Prevalence, incidence, and classification of epilepsy in the Faroes.

In a retrospective study covering 11 years (1970-80) the annual incidence of epilepsy in the isolated population of the Faroes (approx. 43,000 inhabitants) was found to be 42 per 100,000. The prevalence of all types of epileptic seizures has been found to be 763 per 100,000 on prevalence day, December 31, 1980. The relative frequency of different types of epilepsy in accordance with the International Classification of Epilepsies (1969) is reported.

Adolescent↗
PubMed1982

Chronic paroxysmal hemicrania: continued remission of symptoms after discontinuation of indomethacin.

Discontinuation of indomethacin in chronic paroxysmal hemicrania (CPH) usually causes relapse of symptoms within a few days. A patient with characteristic symptoms of CPH is reported. The patient had daily attacks of unilateral headache accompanied by ipsilateral lacrimation and conjunctival injection, a frequency of attacks between four and fourteen per day, and never a headache-free day. He was treated with indomethacin, and all symptoms disappeared within 24 h. After three months indomethacin was discontinued. Six months after that the patient was still symptom-free.

Aged↗
PubMed1982

Stroke in an isolated population. Incidence on the Faroes during 1962-1975.

In a retrospective study covering 14 years (1962-75), the annual incidence of stroke in the isolated population of the Faroes (approx. 40000 inhabitants) was 45.7 per 100000 in the age range 15-65 years. The type of stroke was subarachnoid haemorrhage in 34 cases, and other types of stroke were found in 111 cases. The incidence of stroke in this study was lower than in Denmark, Finland, Sweden and the USA. There was no significant sex difference (males 43.0, females 48.3) (p greater than 0.05). It is pointed out that dietary habits on the Faroes differ from those in other Scandinavian countries.

Adolescent↗
PubMed1981

Clonazepam (Rivotril) and carbamazepine (Tegretol) in psychomotor epilepsy: a randomized multicenter trial.

The antiepileptic properties of carbamazepine (Tegretol) and clonazepam (Rivotril) were compared in a double-blind randomized study comprising 36 patients with newly diagnosed, untreated psychomotor epilepsy (partial seizures with complex symptomatology). No significant differences were found between the two drugs during the 6 months of treatment. Measurements of concentrations in plasma confirmed that the patients exceeded the accepted lower limit for therapeutic range of the drugs.

Adolescent↗
PubMed1981

Incidence of primary intracranial neoplasms in an isolated population (the Faroese) during the period 1962-1975.

In a retrospective analysis covering a 14-year-period (1962-1975) the annual incidence of primary intracranial neoplasms in an isolated population of about 40,000 (the Faroese) was found to be 9.9 in 100,000. Out of the 52 patients with intracranial neoplasms 20 were alive, while 32 had died when the study was closed on 31st December 1979. Eighteen out of the 34 patients with supratentorial tumours and one patient with acoustic neurinoma had epilepsy.

Adolescent↗
PubMedDate not supplied

Subarachnoid hemorrhage in an isolated population. Incidence on the Faroes during the period 1962-1975.

In a retrospective study of a 14-year period (1962-1975) the annual incidence of subarachnoid hemorrhage (SAH) was found to be 7.4 per 100,000 in an isolated population of about 40,000. The age-specific incidences in the age groups from 15-25 to 60 years are on the same level as found in Sweden, Rochester USA, England, and Iceland, but lower than the findings in Finland. The age-specific incidence among persons over 60 years of age was far lower than in Sweden, Rochester USA, and Finland. The possible causes of the lower incidence in all age groups than reported in the above-mentioned studies are discussed. Forty patients had a history of SAH. Two months after the episode 38% had died and at the end of 5 years 53%. The recurrence rate at 5 years was 24%.

Adolescent↗