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Biomedical subjects

P Juul-Jensen

Publications and source records attributed to P Juul-Jensen.

At least 19 recordsLinked to original sources
PubMed1983

Natural history of epileptic seizures.

Since 1963 a continuous registration of patients with epileptic seizures has been carried out in Greater Aarhus, Denmark. This registration has been attempted by means of medical records dating back to 1940. On the basis of the established prevalence and the calculated cumulated incidence, we have tried to describe the natural history of the different types of epilepsy. The prevalence of all types of epileptic seizures (including febrile convulsions) has been found to be 2,441/100,000, whereas for patients with the diagnosis of epilepsy the rate is 1,274/100,000. The study describes the natural history of the different types of epilepsy. In addition, the risk-increasing effect of a febrile convulsive seizure on the development of epilepsy is analyzed.

Adolescent↗
PubMed1979

Neurological, electroencephalographic and neuropsychological examination of 53 former amateur boxers.

The purpose of the present study was to reveal possible neurological sequelae of amateur boxing after the introduction of modern medical supervision and safety precautions. Neurological, electroencephalographic and neuropsychological examinations were performed in a total of 53 former champion amateur boxers together with a control group consisting of 53 former football players. The football players were, on an average, better educated than the boxers, but otherwise the two groups were comparable. Complaints, neurological findings and electroencephalographic changes were identical in the boxers and control group. Only minor neuropsychological disturbances were found in the boxers most pronounced in impaired motor function of the left hand. This was further demonstrated by comparing 19 pairs, each consisting of one boxer and one football player, matched according to age, education and vocabulary. No relation between abnormal findings and "occupational exposure" during the boxing career could be demonstrated, not even by comparing three pairs of identical twins, although in each twin of the pairs there was a great difference in the number of fights. This study provides no basis for legislation against amateur boxing at the present time, as it indicates that the existing safety precautions protect the boxers against serious and permanent brain damage.

Boxing↗
PubMed1978

Somatostatin in the treatment of patients with extra-pyramidal disorders and patients with EEG abnormalities.

The growth hormone release inhibiting hormone acts probably both as a true hypophysiotropic hormone and as a neuroregulatory substance. Neurophysiological studies have shown that somatostatin is a CNS depressant. Somatostatin might therefore be of therapeutic significance in neurological diseases. Sixteen patients with different extrapyramidal disorders and seven patients with various EEG abnormalities were tested with 2-hour somatostatin infusions and control infusions with saline. Somatostatin did not induce any improvement or deterioration of symptoms, signs, or EEG abnormalities in any patient.

Adult↗
PubMed1975

EEG in unilateral and bilateral electroconvulsive therapy.

The investigation concerned 100 patients with endogenous depression treated with ECT, 52 unilaterally on the non-dominant hemisphere, and 48 bilaterally. A double-blind investigation of the therapeutic effect and the effect on memory and on EEG was carried out. With unilateral treatment, mainly diffuse and same-sided EEG changes appeared, while with bilateral treatment mainly diffuse and left-sided changes occurred. Bilateral treatment led to significantly more EEG changes than did unilateral treatment. For both groups there was a tendency to greater changes after the last than after the sixth treatment. At termination of treatment, a significantly better therapeutic effect was found in cases where EEG changes appeared, especially severe EEG changes. This applied to the total material but not to the groups of unilaterals and bilaterals taken separately. In the entire material after the first six treatments, the greatest representation of patients with unchanged and impaired memory was found in cases with deteriorated EEG compared to cases with no EEG deterioration. After the entire series of ECT, this correlation no longer was present. After separation of the patients into unilaterals and bilaterals it was not present at any of the stages. In the bilateral group ECT treatment gave more frequent and stronger EEG changes, among the older than among the younger patients. For the unilateral group, there was no comparable difference. The number of weak seizures was significantly greater among the unilaterals than among the bilaterals. The therapeutic effect was not correlated to the number of weak seizures, but the number of weak seizures was positively correlated to the number of treatments applied.

Adult↗