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Biomedical subjects

P K Beredjiklian

Publications and source records attributed to P K Beredjiklian.

18 recordsLinked to original sources

Arthroscopic electrothermal collagen shrinkage for symptomatic laxity of the scapholunate interosseous ligament.

The medical records, radiographs and operative reports of ten consecutive patients of average age 37 (range 19-67) years with wrist pain secondary to structural disruption of the scapholunate interosseous ligament (Geissler Type 2 injuries) who were treated with wrist arthroscopy and electrothermal collagen shrinkage of the scapholunate interosseous ligament were reviewed. Functional outcomes were assessed using the DASH scoring system at an average follow-up of 28 (range 12-44) months. At latest follow-up, nine patients (90%) were asymptomatic and had returned to their pre-injury functional level. The mean score on the DASH questionnaire was 20 (range 11-48). One patient developed wrist discomfort and mechanical symptoms 7 months postoperatively and required revision surgery. Our preliminary findings suggest that this may be a viable treatment option in the management of patients with symptomatic scapholunate interosseous ligament laxity without complete ligament disruption. Additional study is needed to better understand the role of this treatment modality.

Adult↗

Evaluation of the sigmoid notch with computed tomography following intra-articular distal radius fracture.

A classification system for disruption patterns of the sigmoid notch of the radius associated with distal radius fractures has not been established. Using plain x-rays and corresponding computed tomography (CT) scans we characterized and quantified the types of sigmoid notch involvement in 20 consecutive distal radius fractures with radiocarpal joint extension. Plain radiographs revealed fracture extension into the sigmoid notch in only 7 cases (35%) and the CT scans demonstrated fracture extension into the sigmoid notch in 13 cases (65%). Of the 13 fractures with sigmoid notch involvement, 9 (69%) were displaced and 4 (31%) were nondisplaced. Sigmoid notch articular step-off (n = 7) and gapping (n = 9) were detectable on the CT scans but not on the x-rays. Plain x-rays appear to underestimate sigmoid notch involvement following distal radius fractures. In addition, CT appears to be a superior diagnostic modality for quantifying sigmoid notch fracture step-off and articular gapping.

Adult↗

Computed tomography scanning of intra-articular distal radius fractures: does it influence treatment?

The purpose of this study is to determine whether the addition of computed tomography (CT) results in changes in the evaluation and treatment of intra-articular distal radius fractures. Fifteen intra-articular distal radius fractures were evaluated independently by 4 hand surgeons. Plain x-rays were reviewed initially followed by the corresponding CT scans for comparison of articular step-off and gapping, comminution, and treatment. Kappa coefficients (kappa) of intraobserver and interobserver reliability for treatment plans were generated. Computed tomography scans improved the sensitivity of measurement of articular surface gapping, improved the accuracy of detection of comminution and distal radioulnar joint involvement, and altered proposed treatment plans within observers (intraobserver agreement: kappa =.54, moderate) and improved agreement of proposed treatment plans between observers (kappa =.34 to kappa =.44, fair to moderate). Computed tomography scanning influenced observers to change treatment plans and resulted in increased interobserver reliability in the proposed management of these injuries.

Humans↗

Effects of forearm rotation on the clinical evaluation of ulnar variance.

Neutral rotation radiographs of the wrist are recommended to standardize the measurement of ulnar variance because it is known that changes in forearm rotation result in changes of this measurement. The purpose of this study was to examine whether there are clinically measurable differences in ulnar variance between radiographs in various degrees of forearm rotation in human subjects. Forty-five wrist radiographs of 15 normal adults were obtained in 3 positions: maximum forearm pronation, neutral rotation, and maximum supination. The ulnar variance on each view was measured by 3 independent observers using a standard millimeter ruler. The average absolute difference in ulnar variance was 0.4 mm between pronation, 0.6 mm between pronation and supination, and 0.2 mm between neutral and supination. Although we found a statistically significant difference in ulnar variance between the pronated and neutral positions, this difference may not be clinically significant and may not justify concerns of forearm position during the radiographic evaluation of ulnar variance.

Adult↗

Nodular fasciitis of the hand: a case report.

Nodular fasciitis is a benign, reactive fibroblastic soft tissue tumor. Involvement of the hand is exceedingly rare. A case of nodular fasciitis involving the dominant hand of a 38-year-old woman is reviewed, and its clinicopathologic features are presented. Because of its rapid growth and aggressive histologic appearance, nodular fasciitis can be mistaken for a soft tissue sarcoma, despite its benign clinical behavior. For this reason, aggressive surgical resection should be avoided.

Adult↗

Prevertebral abscess with extension into the hip joint.

We present a case of a paravertebral abscess with extension into the hip joint. The presumed conduit of infection in this case is the iliopsoas bursa, which has been shown to provide direct communication between the retroperitoneal space and the hip joint in up to 15% of cadaveric specimens. The patient was treated with emergent open irrigation and debridement of the hip joint, as well as percutaneous drainage of the prevertebral abscess. The patient remains minimally symptomatic at the 2-year follow-up.

Abscess↗

Intra- and interobserver reliability of sensibility testing in asymptomatic individuals.

Threshold and innervation density tests are common clinical tools used in the evaluation of peripheral nerve injuries and compression syndromes. The purpose of this study is to determine the inter- and intraobserver reliability of Semmes-Weinstein monofilaments and static and moving two-point discrimination in 48 volunteers. Kappa coefficients of inter- and intraexaminer agreement were generated for each test and investigator. The interexaminer reliability for the Semmes-Weinstein monofilaments ranged from fair to moderate in the ulnar and median nerve distributions, and slight to moderate in static and moving two-point discrimination testing. Intraobserver reliability for Semmes-Weinstein monofilaments and static and moving two-point discrimination was slight to fair for both examiners. Our data indicate that Semmes-Weinstein monofilaments and two-point discrimination tests yield unreliable measurements in asymptomatic individuals. Although useful in monitoring neurological function in pathological states, threshold and innervation density measurements from an unaffected digit or extremity may not represent a reliable standard for comparison of abnormal values.

Adult↗

Evaluating the source and content of orthopaedic information on the Internet. The case of carpal tunnel syndrome.

BACKGROUND: The Internet has become a popular source of medical information for patients. Authors of health-related web pages are not required to adhere to any standard for medical content or accuracy. The goal of the present study was to assess the type, quality, and reliability of information about carpal tunnel syndrome that is available on the Internet. METHODS: The search phrase "carpal tunnel syndrome" was entered into five commonly used World Wide Web search engines. The search results then were given as an ordered list of universal resource locators, or web-site addresses. The top (first) fifty web sites from each of the five searches were combined to create a master roster of 250 web-site addresses. These web sites then were evaluated for authorship and content, and an informational value score ranging from 0 to 100 points was assigned to each. RESULTS: Thirty-three percent of the sites sold commercial products for the evaluation or treatment of carpal tunnel syndrome. An additional 30 percent were commercial web sites that did not sell products. Only 23 percent of the sites were authored by a physician or an academic organization. Fewer than half of the sites offered conventional information. Twenty-three percent of the sites offered unconventional or misleading information. The mean informational value of the web sites was 28.4 of a possible 100 points. CONCLUSIONS: The information about carpal tunnel syndrome on the Internet is of limited quality and poor informational value. The public and the medical communities need to be aware of these limitations so that the quality of medical information available on the World Wide Web can be improved.

Carpal Tunnel Syndrome↗

The significance of the three volar spaces in forearm compartment syndrome: a clinical and cadaveric correlation.

The goal of this study was to assess the importance of the 3 volar spaces in forearm compartment syndrome in a prospective manner. A cadaveric model was developed to correlate with our clinical experience. All but 1 of 21 volar compartments (superficial volar, deep volar, and pronator quadratus spaces) in 7 patients in our clinical series decompressed adequately after release of the superficial volar fascia. One patient needed further release of the pronator quadratus compartment; he had suffered a combined crush and vascular injury. All volar compartments in our cadaveric model decompressed with superficial fasciotomy. Prefasciotomy and postfasciotomy pressures should be obtained from all 3 compartments of the volar forearm. Superficial fasciotomy usually adequately decompresses the entire volar forearm; however, in the event that deep compartment pressures remain high after superficial fasciotomy, release of the affected space is indicated.

Adult↗

Operative treatment of malunion of a fracture of the proximal aspect of the humerus.

We retrospectively reviewed the medical records, operative reports, and preoperative and postoperative radiographs of thirty-nine patients who had been managed operatively for malunion of a fracture of the proximal aspect of the humerus. The malunions were categorized according to the presence of osseous abnormalities, including malposition of the greater or lesser tuberosity (type I; twenty-eight patients), incongruity of the articular surface (type II; twenty-six patients), and malalignment of the articular segment (type III; sixteen patients). Soft-tissue abnormalities, such as soft-tissue contracture, a tear of the rotator cuff, and impingement, were also recorded. At an average of forty-four months (range, twelve to fifty-three months) postoperatively, the patients were assessed for pain relief, the range of motion of the shoulder, and the ability to perform activities of daily living. The result was satisfactory for twenty-seven patients (69 per cent) and unsatisfactory for the remaining twelve (31 per cent) at the latest follow-up evaluation. Of the twenty-seven patients who had a satisfactory result, twenty-six (96 per cent) had had complete operative correction of all osseous and soft-tissue abnormalities. Of the twelve patients who had an unsatisfactory result, four had had complete operative correction of these abnormalities (p < 0.0001). Twenty-six patients (67 per cent) had incongruity of the glenohumeral joint at the time of presentation. Twenty-three of these patients had the incongruity corrected with prosthetic arthroplasty (twenty-two) or arthrodesis of the glenohumeral joint (one); the result was satisfactory for seventeen (74 per cent). In contrast, the result was unsatisfactory for all three patients in whom the incongruity had not been corrected at the time of the operation (p = 0.01). Eleven patients had malposition of the greater or lesser tuberosity but a congruent joint surface preoperatively. Ten patients in this group were managed with either osteotomy of the tuberosity or acromioplasty, and nine of them had a satisfactory result at the latest follow-up evaluation. The result was unsatisfactory for one patient who was managed with only correction of a soft-tissue contracture (that is, no treatment of the malposition) (p = 0.05). Both osseous and soft-tissue abnormalities were identified as the cause of pain and stiffness in patients who had malunion of a fracture of the proximal aspect of the humerus. We concluded that operative management of these patients is successful only if all osseous and soft-tissue abnormalities are corrected at the time of the operation.

Acromion↗

Prosthetic radial head components and proximal radial morphology: a mismatch.

A morphometric study of the proximal radius was performed with magnetic resonance imaging scans to measure the anatomic dimensions of the radial head and neck. These dimensions were then compared with the manufacturer's size specifications of commercially available titanium prosthetic radial head components to determine whether these designs adequately match the morphologic characteristics of the proximal radius. A cadaveric correlation was performed to validate the accuracy and reliability of measurements obtained from the magnetic resonance scans. The narrow intramedullary dimensions of the radial neck negated fitting of even the smallest available metallic prosthetic component stem in 18 (39%) of 46 scans reviewed (confidence interval 26% to 53%). Of the 31 male patients who underwent scanning, 4 (13%) would not be able to be fitted with a prosthetic component according to the manufacturer's technique guide (confidence interval 0% to 29%). Of the 15 female patients who underwent scanning, 14 (93%) would not able to be fitted with a prosthetic stem (confidence interval 70% to 99%). In those patients in whom the radial neck could accommodate a prosthetic stem (n = 26), there was ineffective restoration of proximal radial head length in all cases (100%, confidence interval 87% to 100%). The average shortening was 4 mm of proximal radial length (range 1 to 7 mm). Our findings reveal that the commercially available metallic radial head design may overestimate the dimensions of the radial neck. Inadequate sizing of radial head prostheses may lead to an inadvertent change in proximal radial length, with potentially adverse effects on elbow, forearm, and wrist mechanics. Newer designs taking into account these anatomic dimensions may lead to an improvement in function after reconstruction.

Adolescent↗

Orthopaedic manifestations of chronic graft-versus-host disease.

Chronic graft-versus-host disease (GVHD) is a well-recognized complication of allogeneic bone marrow transplantation (BMT). Musculoskeletal manifestations include joint contractures, polymyositis, polyserositis, and fasciitis. We present 14 patients with orthopaedic complications of chronic GVHD. Long-term conservative management of joint contractures with physical therapy and orthotics was generally successful in restoring patients' premorbid functional status. Surgical release of joint contractures yielded poor results and rendered the affected joints unresponsive to further conservative treatment. Surgical intervention in the treatment of joint contractures resulting from chronic GVHD does not appear qualitatively to improve functional status in patients affected with this disease process.

Adolescent↗

Computed tomographic scanning of cervical spine fractures: does it influence treatment?

OBJECTIVE: To determine whether the superior sensitivity of computed tomography (CT) results in changes in treatment plans for cervical spine fractures that have been diagnosed on plain films alone. DESIGN: Retrospective review of radiographic studies for cervical spine trauma. SETTING/PARTICIPANTS: An orthopaedic spine surgeon (SS), an orthopaedic traumatologist (OT), an orthopaedic spine fellow (SF), and an orthopaedic chief resident (CR) were independently presented thirty-nine cases of cervical spine trauma imaged with adequate plain radiographs and with CT. MAIN OUTCOME MEASURES: Agreement was measured by calculation of kappa coefficients. RESULTS: The detection rate of total fractures on plain radiographs alone ranged from 47 percent to 71 percent, and the diagnosis changed an average 53 percent of cases. Change in treatment plans ranged from 10 percent (SS) to 46 percent (CR) of cases. Of these changes, undertreatment occurred as follows: SS =3 percent, OT =8 percent, SF =36 percent, and CR = 46 percent. The mean kappa coefficient for intraobserver agreement of treatment plans was 0.69. The experienced observers demonstrated "excellent" agreement with an average kappa coefficient of 0.85, whereas the mean coefficient for inexperienced observers was 0.54 or "moderate" agreement. Complete diagnostic agreement occurred between the experienced observers after review of both the plain films and CT scans. The interobserver agreement of treatment plans for the experienced observers increased from 0.79 to 0.88. CONCLUSIONS: CT scanning afforded additional information for all observers. Experienced observers can reliably determine treatment plans for cervical spine trauma diagnosed on plain films alone, whereas inexperienced observers are less reliable. For the experienced observers, interobserver agreement on treatment plans increased after the addition of CT.

Cervical Vertebrae↗