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Biomedical subjects

P K Bjerre

Publications and source records attributed to P K Bjerre.

7 recordsLinked to original sources
PubMed1997

[Endovascular occlusion of intracranial aneurysms using the "Guglielmi Detachable Coil"].

Thirty-seven patients with 42 sacculate intracranial aneurysms of delicate location were treated, or attempted treated, with Guglielmi Detachable Coils (GDC) from July 1994 through December 1995. Intended aneurysm occlusion was not achieved in five patients (five aneurysms) due to unfavourable anatomy. In two additional cases the procedure was interrupted because of complications. In 31 patients (35 aneurysms) the aneurysms were successfully occluded. So far 16 patients (19 aneurysms) have undergone angiography six months postoperatively, and four of five partly recanalized aneurysms were reoccluded. Two patients died following a major complication, and five patients recovered following a minor complication to the procedure. A total of 39 procedures were uncomplicated, and the patients recovered uneventfully. In conclusion, endovascular occlusion with GDC of intracranial aneurysms of delicate location is a promising innovative procedure.

Adolescent↗
PubMed1997

Effect of glucocorticoids on ICP in patients with a cerebral tumour.

Preoperative treatment with glucocorticoids in patients with an intracranial tumour has been neurosurgical practice for more than 30 years. Recently, however, a less beneficial effect in patients with a meningeoma is reported. This study included 4 patients with a glioma, 4 with a metastasis and 5 with a meningeoma. All patients had a substantial amount of oedema. The effect of methylprednisolone was monitored during 5 days by clinical examination and epidural pressure measurement. ICP reduction was found in 4 of 13 patients. All observations of decreasing pressure were in patients with a malignant tumour and an initial ICP > 15 mmHg. All 4 patients improved clinically. Another 4 patients with a benign meningioma had a significant increase of ICP and none of them experienced clinical improvement. Clinical deterioration was not observed in any patient despite increasing ICP in some cases. In summary, a beneficial effect of GC was demonstrated only in patients with a malignant tumour and augmented pre-treatment ICP.

Brain Edema↗
PubMed1993

[Endovascular neuroradiologic interventions. Embolization of aneurysms and arteriovenous malformations. Sclerotherapy of cavernous hemangiomas].

Endovascular interventional neuroradiology was introduced less than 20 years ago, and has since then evolved to be an established treatment. Endovascular embolization is particularly well-suited for treatment of patients with intra/extracranial arterio-venous malformations, arteriovenous fistulae and inaccessible arterial aneurysms. Initiated through cooperation with a French team we have until now at the Radiological Department, Odense University Hospital, treated a total of 13 patients (one year). Eight arterio-venous malformations or fistulae have been completely (three patients) or partially (five patients) occluded with Histoacryl glue. In two other patients the internal carotid artery has been occluded with detachable balloons. Three additional patients with an extracranial cavernous hemangioma have been treated with direct puncture and injection of sclerosing agent (Alcohol) into the lesion, with resulting shrinkage of the lesion in all patients. Non-intended embolization of an artery was observed in one case. Endovascular interventional neuroradiology, especially embolization, is a step forward in the treatment of delicate vascular lesions in the brain and face.

Adolescent↗