PubMed Health⌕ Search

Biomedical subjects

P K Goldstein

Publications and source records attributed to P K Goldstein.

4 recordsLinked to original sources
PubMed1987

Sodium bicarbonate reduces viability and alters aflatoxin distribution of Aspergillus parasiticus in Czapek's agar.

The potential of sodium bicarbonate to inhibit growth of and aflatoxin synthesis by Aspergillus parasiticus was examined in Czapek's agar (CA), a medium in which fluorescence under UV light indicates aflatoxin production. Incorporation of sodium bicarbonate (SB) into CA at 0.011, 0.022, and 0.033 mol% reduced cell viability 63-, 10(3)-, and greater than 10(7)-fold, respectively. Colonies resulting from surviving cells did not fluoresce under UV light, but thin-layer chromatography analysis of culture extracts detected aflatoxins. Potassium bicarbonate (KB) at 0.011 and 0.022 mol% produced inhibitory effects similar to those of SB, but NaCl and silica had no effect. After 7 days, control cultures had the normal aflatoxin distribution (B1 greater than G1 greater than B2 greater than G2), but this distribution shifted to B2 greater than B1 approximately equal to G2 greater than G1 during prolonged incubation. Cultures supplemented with SB and KB contained mostly aflatoxins B1 and G1 after 28 days. Both SB and KB raised the pH of CA to 7.5 to 8.5 at the time of growth. Culture growth on CA adjusted to pH 7.5 to 8.5 with NaOH was not inhibited but exhibited reduced fluorescence and elevated levels of aflatoxins B1 and G1. Thus, while bicarbonate inhibition of growth could not be attributed to pH elevation, the lack of culture fluorescence on CA-SB and CA-KB and the altered aflatoxin distribution were caused by the ability of SB and KB to elevate pH.

Aflatoxins↗
PubMed1982

Roles and functions of the occupational therapist in the treatment of sensory integrative dysfunction. Official position paper.

Occupational therapy is based on the belief that purposeful activity may be used to prevent and remedy dysfunction, and elicit maximum adaptation toward achieving optimum functioning. Fundamental to a person's ability to interact with the environment is the ability to process sensory information. The theories and research related to sensory integration have provided te basis for the development of a therapeutic model used by occupational therapists in their efforts to help individuals reach their potential for productive, purposeful lives.

Humans↗
PubMed1981

A learning disability screening program in a public school.

The outline of screening program for learning disabilities in a public school is presented in this paper. The screening program consisted of four standardized measures (Information Subtest of the WPPSI, SEARCH, Evanston Early Identification Scale, Bender-Gestalt) and six of the clinical observations suggested by Ayres. Forty-three kindergarten and first graders (25 males, 18 females) were tested and each child was categorized as low, moderate, or high risk for learning disabilities on each of the measures. Approximately 10 percent of the children were identified as at high risk for learning disabilities, but the children did not perform at the same risk level on all measures. A factor analysis of the four measures and six observations revealed that three factors prevailed in this screening program; cognitive abilities, fine motor control, and reflex integration. This analysis also indicated the importance of assessing neurophysiological immaturity in a screening program. The implications of the categories used are discussed.

Aptitude Tests↗