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P K Hanashiro

Publications and source records attributed to P K Hanashiro.

10 recordsLinked to original sources

Hyperventilation. Benign symptom or harbinger of catastrophe?

Hyperventilation is a common feature of many acute clinical conditions that can be benign or potentially catastrophic. The symptoms accompanying hyperventilation are diverse and non-specific, reflecting a physiologic state of hypocapnia secondary to alveolar overventilation. Results of arterial blood gas analysis confirm hypocapnia and may lead to identification of the clinical cause, with pH or PaO2 measurements indicating acid-base abnormalities or hypoxemia. Treatment should be directed at correcting the underlying clinical condition. In patients whose hyperventilation is caused by anxiety states, anxiolytic drug therapy in the acute phase should be followed by education, reassurance, retraining to change breathing patterns, and psychotherapy.

Adult

Cardiopulmonary resuscitation. A current perspective.

Cardiopulmonary resuscitation is effective if established early and coupled with specific therapeutic interventions. Most cardiopulmonary arrest is due to ventricular fibrillation and early defibrillation offers the highest probability of success. External cardiac compression alone is inadequate to provide adequate perfusion to vital organs and, therefore, cannot sustain life unless coupled with advanced therapeutic interventions. Many new techniques for increasing flow have been developed, but have not been established clinically. The American Heart Association guidelines for CPR are still valid and are the basis for our current CPR. A practical perspective is presented whereby the therapeutic interventions are pursued systematically in an expeditious and coordinated fashion so that the key interventions are made within the first 10 to 15 minutes of the arrest.

Anti-Arrhythmia Agents