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Biomedical subjects

P K Pathak

Publications and source records attributed to P K Pathak.

6 recordsLinked to original sources
PubMed1989

Prognostic significance of pre discharge one hour electrocardiographic monitoring in patients recovering from acute myocardial infarction.

During a 15 months period, 97 patients with AMI were monitored continuously at hospital discharge for one hour. The VPCs or no VPC noted during this period of continuous monitoring were correlated with subsequent cardiac events during one year follow up. Patients with complicated VPCs had a significantly higher incidence of cardiac deaths and non-fatal re-infarctions during one year follow up (54.5%) as compared to patients with no VPCs (6.5%) (p less than .001). Patients with higher grades of VPCs had more complicated course (30.3% to 66.7% for Lown Grade II to IV) as compared to 6.5% and 20.8% for grade Lown O and I. Though, the results of this 1 hour continuous monitoring at hospital discharge are not as sensitive as with ambulatory Holter monitoring as is evident from this study where complicated VPCs were detected in 11.4% patients vs. 33% with Holter monitoring, it could be a useful tool in institutions where the facility of Holter monitoring does not exist.

Adult↗
PubMed1981

Kala-azar hits again.

Six hundred and ninety-two cases of kala-azar were studied, all confirmed cases. Vaishali, Muzaffarpur, Samsatipur and Sitamarhi were the most affected districts of Bihar. Fever, weight loss, hepatosplenomegaly, anaemia, leucopenia and monocytes were the most commonly found features, whereas pigmentation of skin was found in only 4.48% of cases. Lymphadenopathy and voracious appetite were conspicious by their absence. Study of the incubation period of the disease showed that it may be as short as 24 h. Bone marrow study revealed hypoplastic marrow with increase in the cells of the monocytic series. Serum electrophoresis revealed reduction in albumin and rise in globulin, leading to decrease in A : G ratio. Tuberculin test was negative in the majority of the patients.

Adolescent↗