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Biomedical subjects

P K Schmidt

Publications and source records attributed to P K Schmidt.

At least 19 recordsLinked to original sources
PubMed1991

[Experiences with color-coded duplex sonography in the diagnosis of extracranial vascular changes].

72 Patients with occurred transitory ischemie attacks and passed reversible neurologie deficits were duplexsonographically diagnosed. After wards a renewed duplexsonographic investigation with color coding followed in all patients. The patients were angiographically diagnosed within two weeks. As a result in three of ten patients with an unobtrusive angiogramm plaques formations were proved by means of the color codes duplexsonography.

Adult↗
PubMed1991

[Value of color-coded duplex sonography in diagnosis of extracranial vascular changes].

72 patients at the age of 44 to 76 years with transitory ischaemic attacks which happened and for a short time reversible deficits, respectively, were diagnosed both conventionally duplex-sonographically and with the colour-coded duplex sonography under the question of vascular stenotic process in the region of the cervical vessels. After the ultrasound examination within two weeks an angiography was performed. As a result was shown that in 10 patients with an angiogram without pathological findings by means of the colour-coded duplex sonography in 3 cases plaque formations could be proved which could be clearly diagnosed only by colour marking.

Adult↗
PubMed1991

[Acute and long-term effects of pimobendan (UD-CG 115) in NYHA II and III heart failure. Results of a randomized multicenter double-blind study].

The effects of pimobendan (UD-CG 115) on hemodynamics and exercise capacity after acute (single dose) and chronic (6 month) oral treatment, as well as acute treatment after 6 months were investigated in 67 patients with chronic heart failure of NYHA classes II or III, which had persisted in spite of treatment with diuretics and digitalis. They were treated with pimobendan (2.5 mg bid or 5 mg) or placebo in a randomized, double-blind multicenter trial. With a single administration before and after 6 months' treatment there was-compared to placebo-a significant fall in pulmonary capillary pressure (PCP) at rest (R) and during exercise (E) of 7% to 24%. Right atrial pressure (R) and pulmonary arterial pressure (PAP) (R, E) decreased after pimobendan on day 1; cardiac index (E) increased significantly. All other parameters were not influenced. After chronic therapy, PCP (E), PAP (E), LV stroke work index (E), and pulmonary resistance (R and E) values were significantly lowered by pimobendan when compared to day 1. Exercise duration was prolonged after 6 months by 83 s and 47 s after 5 and 10 mg/day, resp., compared to the placebo group (group difference not significant). Subjective wellbeing was improved in all three groups (no group difference). Clinical symptoms were not altered; six patients (two in each group) died suddenly. Another nine patients discontinued the trial prematurely because of poor efficacy or adverse events (no group difference). Overall, pimobendan was well-tolerated and had favorable effects on both acute and chronic hemodynamics and on exercise capacity. There was no evidence of any tolerance development.

Adult↗
PubMed1991

[Experiences with the Günther filter].

In the investigation 17 patients with lung embolism being cared for with a Guenther-filter were post-observed during a period up to two years. Early complications after the implantation of the Guenther-filter did not occur in any case. Late complications after the implantation of the Guenther-filter were dislocations, deformations of the filter and breaks of the spokes. In the result of the post-observation the Guenther-filter application despite its easy handling should be regarded very critically.

Aged↗
PubMed1990

[Results of using EEG and carotid angiography for evaluating cerebrovascular insufficiency].

In the cerebrovascular disease the EEG can give references at localisation, extension and course. The ability of statement is increased by methods of provocation and activation. On 35 patients with cerebrovascular insufficiency can be indicated that there are good correlations between changes on the large cerebral supply vessels and changes of the EEG, in particular in the carotid pressure trial.

Adolescent↗
PubMed1990

[Doppler sonography in the diagnosis of extracranial vascular changes].

On account of cerebrovascular insufficiencies or asymptomatic vascular noises which had taken place 45 patients were examined by means of Doppler sonography and after this by means of angiography. The judgement of the common carotid artery, the internal and external carotid arteries, the vertebral artery, the subclavian artery and the supratrochlear artery were involved into the ultrasound investigation. The sensitivity of the supratrochlear compression test was 50% in the diagnosis of high-degree stenoses and occlusions of the internal carotid artery, whereas the sensitivity of the complete ultrasound investigation way about 80%. The advantages and disadvantages of the ultrasound Doppler sonography investigation are discussed.

Adult↗
PubMed1990

Trace element-hormone-relations in the early course of myocardial infarction.

In 30 patients suffered from acute myocardial infarction the serum levels of zinc, copper, cortisol, aldosterone, and triiodthyronine were determined. Zinc and triiodthyronine decrease, the other parameters increase. The serum levels of the tested parameters show a characteristic course within the first days after onset of myocardial infarction. There are significant differences between patients without complications and patients with complicated course inclusive of deaths. The differences exist already on the day of admission. Therefore we conclude zinc, copper, cortisol, and aldosterone levels as well as the course of T3 level are useful for prognosis of the clinical progress fo AMI. The tested parameters are helpful in differential diagnosis of chest pains caused by myocardial ischemia with or without myocardial infarction. The strong correlations between trace elements and hormones show new aspects due to the explanation of pathological alterations of serum levels in clinical medicine.

Aldosterone↗
PubMed1990

Static and dynamic differences among five types of skinfold calipers.

Thirty-eight skinfold calipers were compared in terms of dial accuracy, downscale force, and pressure at jaw openings of 10, 20, 30, 40, and 50 mm. Dynamic measures were made on four thicknesses of foam rubber. Foam rubber was used to simulate the compressibility of skinfolds and to eliminate subject and tester variability. Five caliper types were tested: 10 Harpenden (HRP), 9 Lange (LNG), 12 Slim Guide (85SG), 4 Skyndex (SKN), and 3 Lafayette (LF). Within-type variation was small and consistent across openings for dial accuracy, force, pressure, and foam rubber compressed thickness. Between-type pressures differed (p less than 0.01), with the HRP and LNG calipers having the highest but similar pressures and the SKN, LF, and 85SG calipers having the lowest but similar pressures. LF and LNG calipers (which differed from each other) had higher compressed foam rubber means than HRP, SKN, and 85SG calipers (p less than 0.01), which were similar to each other at three of four thicknesses. When average pressure was used as the covariate, differences between types were still large, with 97.5-99.3% of the variation explained by type. Compressibility of foam rubber was shown to be caliper specific. It is concluded that there are static and dynamic differences between the five major types of skinfold calipers. When measurer error is eliminated, the HRP, 85SG, and SKN calipers are similar to each other, but they give lower values than the LNG or LF calipers by approximately 50-100%, depending on compressed thickness. These differences should be noted when comparing skinfolds measured with dissimilar calipers.

Anthropometry↗
PubMed1988

[Lyme borreliosis--a possible cause of atrioventricular block].

Eight cases of Lyme borreliosis of clinical certainty with carditis are reported. In six patients, AV-blocks were predominant, two patients had a myopericarditis. Six acute cases were seropositive, but one case remained seronegative. The titer was border-line in that patient, who was studied 4 years after the acute disease. A Lyme carditis should be considered in each case, in which AV-blocks appear acutely.

Adult↗
PubMed1988

[Mechanical properties of a new vena cava filter].

The construction and the mechanical properties of a percutaneous, transvenous implantable thrombus filter on the pulmonary embolism prophylaxis is introduced. The pressure loss by this filter amounted to nearly 1/60 in comparison with the Mobin-Uddin umbrella filter. The effect of partial occlusions by thrombus is estimated theoretically by means of technical models. The anchoring of the fresh implanted filter is guaranteed in case of embolisation with covering up to 85% of the open surface. A much faster anchoring is to be expected by reaction of the tissue after few days. It also resists in the most unfavourable case imaginable.

Blood Vessel Prosthesis↗