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Biomedical subjects

P Kemppainen

Publications and source records attributed to P Kemppainen.

39 records · Page 3Linked to original sources

The influence of naloxone on dental pain threshold elevation produced by peripheral conditioning stimulation at high frequency.

The phasic dental pain threshold elevation produced by high-frequency transcutaneous electrical nerve stimulation (TENS) in healthy humans was not abolished by naloxone. A prolonged (20 min) high-frequency TENS did not cause any tonic pain threshold elevation. The results indicate that opioid-dependent systems have only a minor if any contribution to alleviation of experimental pain during high-frequency TENS.

Adult↗

A critical analysis of the cystic duct remnant.

The cystic duct remnant can be an etiologic factor for distress after cholecystectomy, justifying reoperation and excision of the stump. In connection with cholecystectomy, it is not justified to leave any cystic duct stump unless there is a special reason for it. Stones in the cystic duct remnant, overlooked or newly formed, scar tissues and cystic duct syndrome of whatever cause--inflammation and stasis of the bile, a poorly healing stump end and neuroma--can also be factors producing the discomfort. Unresorbable suture material which provokes foreign body granulomas should be avoided in operations upon the biliary tract since, together with even a normal nerve under pressure, it may cause biliary distress. For the same reason, special attention should be devoted to careful trimming of the cystic nerve in cholecystectomy, and ligation or cautery of nerve tissues should be avoided. The cystic duct remnant is more often visualized in peroperative cholangiography than in an intravenous examination but even then not unfailingly. The cholangiographic finding alone does not justify surgical intervention, since in a number of patients troubles deriving from elsewhere in the biliary tract or from adjacent organs persist and not all cystic stumps apparently produce discomfort.

Adolescent↗