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Biomedical subjects

P Kertész

Publications and source records attributed to P Kertész.

At least 19 recordsLinked to original sources

[Clinical analysis of the sodium-fluoride and sodium-monofluorophosphate content of Colgate toothpaste].

After six weeks use of Colgate toothpaste (1000 ppm MFP and 450 ppm NaF) in case of 50 individuals (25 test and 25 control persons) both the Plaque Index of Silness and Löe and the modified Sulcus Bleeding Index--"bleeding on probing" (Mühlemann and Son) mean values showed a significant decrease. According to the results of cytological testing the effect of toothpaste containing MFP and NaF proved favourable. The investigation of the ionisable plaque fluoride content produced statistically significant rise in plaque fluoride content.

Adult↗

[Pharmacokinetic study of various fluoride compounds in rats].

The fluoride excretion of 40 rats has been monitored after the consumption of drinking water containing NaF, CaF2 and CaF2 + alum (KRl/SO4/2. The fluoride excretion of the animals containing NaF and CaF2 + alum increased in a significant extent. No significant difference could be found in the fluoride excretion of the two groups. Statistically no significant increase has been observed in the fluoride ion excretion after the consumption of CaF2. These results suggest that by systemic intake of CaF2, no CaF2 absorbtion can be observed. So those undesirable gastric mucosa side effects that can be observed or presumed by the intake of NaF and CaF2 + alum are presumably neglibile.

Animals↗

Effect of amine fluoride/stannous fluoride-containing toothpaste and mouthrinsings on dental plaque, gingivitis, plaque and enamel F-accumulation.

The aim of the study was to assess the effect of an amine fluoride/stannous fluoride toothpaste and mouthwash on dental plaque and gingivitis, plaque F- accumulation, F- content and acid solubility of dental enamel. Participants in the 12-week double-blind study were 92 schoolchildren, with a mean age of 12.4 years, randomly distributed to four groups: (1) AmF/SnF2 toothpaste, (2) placebo toothpaste, (3) AmF/SnF2 toothpaste plus AmF/SnF2 mouthwash, (4) placebo toothpaste plus AmF/SnF2 mouthwash. Analyzing the results, the mean values of dental plaque (Silness-Löe index) and of the sulcus bleeding index decreased statistically significantly in all groups except the placebo toothpaste users. Plaque F- and enamel F- content increased considerably only in the two groups using the AmF/SnF2 toothpaste. A decrease in acid solubility was significant only in the group of both test toothpaste and test mouthwash users. Thus the clinical efficacy of the tested AmF/SnF2 toothpaste might be increased by the combined use of mouthrinsings containing the same substances.

Amines↗

The determination of urinary fluoride/creatinine ratio (Q) in monitoring fluoride intake.

Linear correlation (r = 0.6811, p less than 0.001) was found between the 24 hour urinary excreted fluoride quantity and fluoride/creatinine ratio (Q) of the morning urine sample of 21 school children living in a children's home in Hungary. The mean value of fluoride/creatinine ratio (Q) in groups of children from eight different parts of Hungary, also showed linear correlation (r = 0.9720, p less than 0.001) with the measured fluoride concentration of drinking water. The urinary fluoride/creatinine ratio (Q) seems sufficiently informative for controlling fluoride intake in the course of caries preventive field studies.

Adolescent↗

Collaborative WHO xylitol field studies in Hungary. II. General background and control of the dietary regimen.

The consumption of sucrose and xylitol and the exposure to fluoride (F) were analyzed in a field study aimed at assessing the value of peroral xylitol as a caries-preventive measure. The coverage of the general background referred to the conditions of 689 institutionalized children observed for a 3-year-period. The material in the dietary substudy consisted of 286 subjects aged 8-13 years. The intake and excretion of F was monitored at all institutions in a total of 380 children. The frequency of the consumption of sucrose was high, its intake increasing over the weekend in comparison with weekdays. The consumption of the xylitol-containing products did not reduce the frequency of sucrose intake. Varying and fluctuating levels of exposure to systemic F was registered, as also reflected in the urinary F/creatinine quotient.

Adolescent↗

Collaborative WHO xylitol field studies in Hungary. VI. Changes in the carbohydrate to protein ratio of dental plaque.

The carbohydrate to protein ratio of dental plaque was analyzed in a field study assessing the effect of partial substitution of dietary sucrose by xylitol (X group) in comparison with systemic fluoride (F group) and restorative treatment solely (C group). The biochemical analysis was supplemented by quantitative assessment of plaque through the visible plaque index (VPI). The present substudy was carried out cross-sectionally and longitudinally (n = 83) in initially 6- to 11-year-old children. Missing base-line values for the carbohydrate to protein ratio were partly compensated for through reexamination of the carbohydrate to protein ratio 15 months after termination of the trial. The latter series served as reference to indicate the base-line situation. A lower carbohydrate to protein ratio was measured in the X and F groups than in the C group. Improvement of the VPI values was obtained only in the X group. Our results suggest the potential value of parallel quantitative and qualitative assessment of plaque.

Carbohydrates↗