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Biomedical subjects

P L Bhatia

Publications and source records attributed to P L Bhatia.

At least 19 recordsLinked to original sources

Nasopharyngeal carcinoma in Plateau State, Nigeria: a pathological study.

Nasopharyngeal carcinoma is rare in Central Nigeria where it represents 1.7% of all cancers. The prevalence rate is 4 per 100,000 and the male: female ratio is 2:1. Most tumours occur on the left side than the right (4:1) and the mean age at the time of presentation is 44.4 years. Undifferentiated and non-keratinizing carcinomas represent 60% of cases, while well differentiated squamous cell carcinoma accounts for 40%.

Adult↗

Rare infections of nose and paranasal sinuses.

Two cases of fungal infection of the nose and paranasal sinuses by rhinophycomycosis and actinomycosis are reported. The clinical diagnoses in both cases were wrong and in one of them, a malignancy was suspected. These cases are the first to be reported from Central Nigeria. The authors feel that fungal granuloma should be included on the differential diagnoses list for patients with swellings of the nose and paranasal sinuses in this environment.

Adult↗

Aural schistosomiasis mansoni.

Schistosoma mansoni is common in Nigeria as well as in other countries of West Africa (Edington, 1979). The eggs are laid in the small venules of the submucosal layer of the intestinal wall and pass out usually in the faeces but some may enter the blood stream to be found in any organ of the body (Edington et al., 1975). However, a careful search of the available literature failed to reveal any report of schistosomiasis in the ear and hence it was decided to publish this rare case.

Abscess↗

Otolaryngological foreign bodies: a study in Jos, Nigeria.

The incidence of foreign bodies in ears, nose and throat is quite high in Jos Community of Nigeria, 411 cases having been observed over a period of three years. These occurred most frequently in the ears, while the oesophagus was the second commonest site. The foreign bodies were removed in the outpatient or the casualty department in 270 cases (66.7%) while the remaining 141 cases had to be admitted to hospital.

Adult↗

Hypopharyngeal and oesophageal foreign bodies.

Foreign bodies in the food passages are quite common in Jos Community. Majority of 119 cases seen over a period of four years were children 92.4% and a coin was the commonest foreign body (86.5%). The site of lodgement of the foreign body was hypopharynx and abdomen in 11 cases each while 97 were held in oesophagus, mainly in its upper part. Removal of the foreign body by oesophagoscopy was difficult in patients who presented late. The coins formed a pouch in posterior oesophageal wall in six cases while their anterior surfaces got discoloured in 14 cases causing difficulty in their identification. Besides coins in children and dentures in adults, nine patients accidently swallowed a wide variety of foreign objects of different shapes and sizes. Management of such cases has been discussed.

Adult↗

Sensori-neural hearing impairment in chronic granulocytic leukaemia.

Sudden sensori-neural hearing impairment as a complication of chronic granulocytic leukaemia (CGL) occurred in five of the ten patients seen in Jos University Teaching Hospital over a period of two years. This complication occurred more frequently in younger patients especially females with excessive hepatosplenomegaly, higher leucocyte count and lower platelet count. Leucostasis in internal auditory artery may be acting as a thrombus to cause infarction in the cochlea resulting in the sudden hearing loss.

Adolescent↗

Osteonecrosis of hyoid bone and thyroid cartilage.

A 55-year-old man with carcinoma of the right pyriform fossa was treated with cobalt therapy. Subsequently, osteonecrosis of the right greater horn and the right superior horn of the thyroid cartilage developed, followed by pathologic fractures of the processes and spontaneous expulsion of the sequestrae.

Carcinoma, Squamous Cell↗

The radiological features of craniofacial neurofibromatosis.

Three cases of neurofibromatosis are reported showing a wide spectrum of roentgen abnormalities affecting the skull and facial bones. One case had macrocrania and multiple calvarial defects; enlargement of the sella turcica and middle cranial fossa was also present. All the three cases had orbital changes either in the form of enlargement, reduced anteroposterior width or loss of bony outlines with an appearance of emptiness. The other two cases showed predominantly facial involvement with hypoplasia of the mandibular body and ramus, abnormal coronoid process, zygomatic arch, hypoplastic maxilla, cystic mandible with abnormal dentition and absence of the osseous external auditory meatus. Intra-orbital calcification was present in one case. The radiological projections required to evaluate such cases are discussed. The 20 degrees occipito-mental view has been found extremely useful and is recommended.

Adolescent↗