Biomedical subjects
Publications and source records attributed to P L Chigot.
Three pediatric cases of Leri's melorheostosis are reported. Growth disorders and deformities of the limbs are often the first signs in children. X ray shows areas of very opaque condensation of the long bones parallel to the main axis of the bones parallel to the main axis of the bone, and on the epiphyses, small dense and irregular islets. The course is benign but there may be orthopedic complications.
Three pediatric cases of melorheostosis are described. Growth disorders of the limbs are often the first signs in children. The radiological appearance consists of long tracks of increased cortical radiodensity in the long bones and of small dense islets in the epiphyses.
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Study of data concerning calcium and phosphorus after removal of an adenoma in 60 cases of primary hyperparathyroidism, showed that serum calcium levels always fall. Serum phosphorus usually rises, but not always. There is a fall in urinary calcium in cases which previously had increased calcium in the urine. Phosphorus in the urine falls, but in a variable manner. The authors discuss the role of bony lesions and renal failure.
Hyperparathyroidism is able to determine suddenly after a very poor clinical history a deep coma : in such a condition, the diagnosis with the paraneoplastic hypercalcemia may be a difficult one : cervicotomy can be the heroïc way to lead to diagnosis and in the same time to perform treatment. To avoid such a dramatic situation, the authors propose cervicotomy for every patient suspected of P.T.H. adenoma, when calcemia is higher than 115 mg c/l, even if the symptoms are very slight or nil.