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Biomedical subjects

P L Monastyrnaia

Publications and source records attributed to P L Monastyrnaia.

4 recordsLinked to original sources

[The importance of a sequence of laboratory diagnostic micromethods in detecting tumors in subjects with complaints of functional disorders of the gastrointestinal tract].

The paper is concerned with the diagnostic value of a complex of laboratory micromethods for detection of tumors which were used in 421 subjects who had been endoscopically examined for gastrointestinal discomfort. The methods assured correct diagnosis in 61.1% and gave false-positive results in 35.6%. Ninety-seven percent of the latter group showed preneoplastic lesions of the stomach which must be followed up. Half of the patients with preneoplastic lesions of the stomach revealed changes in the physico-chemical properties of blood similar to those observed in gastric cancer patients. False-negative results were obtained in 3.8% of the whole group (far-advanced cancer). The sensitivity of the suggested complex of micromethods for gastric cancer detection was 86%, reliability--61 and specificity--52%.

Biomarkers, Tumor↗

[A method of diagnosing malignant neoplasms based on the natural fluorescence of the blood serum in the ultraviolet and visible regions of the spectrum].

The paper discusses a physico-chemical method for cancer diagnosis by evaluating fluorescence intensity of blood serum in ultraviolet and visible spectra excited by 313-317 nm wavelength monochromatic light. The procedure elicited as much diagnostic evidence as blood-CEA level determination but proved much cheaper, more time-saving and causing less discomfort to the patient. The reliability, sensitivity and specificity of the method in diagnosis of tumors of various histogenesis and site are discussed.

Blood Chemical Analysis↗