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P L Niemel

Publications and source records attributed to P L Niemel.

12 recordsLinked to original sources
PubMed1979

Comparison of cardiolipin and treponemal tests in the serodiagnosis of yaws.

Results of the Veneral Disease Research Laboratory (VDRL), rapid plasma reagin (RPR), Treponema pallidum haemagglutination (TPHA), T. pallidum immobilisation (TPI), and fluorescent treponemal antibody absorption (FTA-ABS) tests on sera of 661 children from a region where yaws is hypoendemic are compared. For 107 (16.2%) out of 661 sera the FTA-ABS test was the only one showing reactivity; in these instances the test was weakly reactive (intensity of fluorescence scored as +) and the children had no history and no signs or symptoms of treponemal disease. A solitary, weakly reactive FTA-ABS test result seems to have no clinical significance in these cases. The FTA-ABS test can be used as a confirmatory test for yaws instead of the TPI test, if only the results of sera showing an intensity of fluorescence scored as ++ or more are considered to be positive. There appeared to be no significant differences in the results of the VDRL, RPR, and TPHA tests as screening tests for yaws when the TPI or FTA-ABS tests were used as reference tests.

Adolescent↗
PubMed1979

Attenuated yaws in Surinam.

Results of a pilot survey in the central, northern region of Surinam indicate that yaws is prevalent (hypoendemic) in this part of the country. No classical symptoms of yaws were seen. The observed lesions were scanty or solitary, dry papillomatous, or macular and scaly, which fits into the clinical picture of attenuated endemic treponematosis.

Adolescent↗
PubMedDate not supplied

Yaws in Suriname.

Frambesia tropica, or yaws, is still prevalent in the urban population of some of the districts in Suriname. In 1911 a campaign against yaws, probably the first such campaign in the world involving treatment with salvarsan, was organized. It resulted in the rapid cure of all hospitalized patients. As a consequence of this success, the disease became less important to the medical authorities in the country. After introduction of penicillin (1945) for the treatment of yaws, the disease almost disappeared in Suriname. After 1970 new cases were diagnosed, and the resurgence of yaws in Suriname became apparent. The symptoms in these cases were attenuated in comparison to those described in standard handbooks. A survey of yaws in the different districts of Suriname was undertaken to determine the prevalence of the disease and its spread through the country in order to plan a new treatment campaign.

Adolescent↗