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P Lamontagne

Publications and source records attributed to P Lamontagne.

9 recordsLinked to original sources
PubMed2001

Quebecers with celiac disease: analysis of dietary problems.

The only known treatment for celiac disease is lifelong avoidance of dietary gluten. For many sufferers from celiac disease, this may be difficult to achieve. The purpose of this study was to analyse dietary habits and related problems of adults afflicted with celiac disease. A questionnaire was mailed to 617 current and former members of the Quebec Celiac Foundation to document health, dietary habits, sources of celiac disease treatment information, daily concerns, and level of difficulty in complying with a gluten-free diet. The final sample size was 234 (75% female). Results indicated that over 35% of participants experienced intestinal discomfort at least twice a week. In addition, 66% felt that their consumption of grain products was insufficient. Only 44% said they had received from dietitians a large quantity of information about celiac disease treatment, and only 57% had a high level of confidence in the information received from dietitians. Thirty-six percent reported difficulty in complying with the gluten-free diet. According to a probit analysis, larger region of residence (p<0.02) and concern about preparing meals (p<0.005) were directly related to difficulty in complying, while older age (p<0.05), satisfaction with gluten-free products (p<0.01), and a high level of confidence in treatment information from gastroenterologists and dietitians (p<0.005) were inversely associated with compliance difficulty. Awareness of these results should encourage dietitians to improve their skills in treating celiac disease.

Adolescent↗
PubMed1997

Immunological and biological properties of recombinant Lol p 1.

BACKGROUND: Current forms of allergy diagnosis and therapies are based on the use of natural allergenic extracts. Despite strong evidence that higher therapeutic efficacy may be achieved with purified allergens, the purification of multiple allergic components from extracts is a fastidious and sometimes an impossible task. However, the use of recombinant allergens may be an alternative to overcome this problem. OBJECTIVE: In this study, we compared the immunological properties of recombinant (r) Lol p 1 with those of the natural protein. METHOD: We cloned directly the gene encoding Lol p 1 from genomic DNA of ryegrass pollen. This gene was subcloned into the expression vector pMAL-c and expressed as fusion protein. Subsequently, rLol p 1 was cleaved from maltose-binding protein using factor Xa. Using binding inhibition and proliferative assays, we assessed the immunological properties of the recombinant allergens. The capacity of rLol p 1 to trigger basophil histamine release and to elicit a skin reaction was also assessed and compared to those of its natural counterpart. RESULTS: We found that the Lol p 1 gene has no introns since we amplified this gene directly from genomic DNA. We demonstrated that the binding sites of anti-Lol p 1 monoclonal antibody, specific human IgG and IgE antibody are well conserved on rLol p 1 as no difference in the binding inhibition profile was observed when using either natural or recombinant protein. At the T-cell level, rLol p 1 elicited a T-cell response in mice comparable to that observed with the natural protein. In addition, we demonstrated that the biological characteristics of rLol p 1 were comparable to those of the natural counterpart, in that rLol p 1 elicited a skin wheal reaction and induced basophil histamine release in grass-allergic patients only. CONCLUSION: The data indicate that natural Lol p 1 and rLol p 1 shared identical immunological and biological properties.

Allergens↗
PubMed1990

The evolution of dental esthetics.

Dental esthetics has been based for a long time, on time-honoured theories where the restored or replaced teeth had to match the face shape while providing due respect to the sex, the age and the personality of the patient. Most of these theories have since been disproved and the standards of dental esthetics have been revised following surveys of naturally perfect smiles and patients' preferences. Guidelines are presented in a sequence of 5 easily applicable steps with the objective of creating the right smile for the right patient.

Adolescent↗
PubMed1978

[Comparative study of 3 irreversible hydrocolloids].

This study was realized: to determine the best manipulation of 3 alginates; to compare their dimensional stability; to compare their reproduction of detail; to evaluate, through these 3 criteria, the best of the 3 alginates. It seems necessary to point out that: The 3 examined alginates show a poor dimensional stability on account of the deformations produced during the setting time and the removal of the impression. The immediate pouring of the model gives the best results, because storing the impression is accompanied by dimensional changes. The other methods of conservation seem considerably less accurate. The reproduction of detail is excellent with the 3 alginates. The accuracy is of 25 micrometer, but it is not possible to take advantage of this quality, because the compatibility and the accuracy of model stone are insufficiently adapted to the properties of the alginates. CA-37 is, among the 3 studied alginates, the one which gave the worst results with regard to the ease of manipulation and compatibility with Vel Mix Stone.

Alginates↗
PubMed1977

[Check plate. 2].

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Dental Occlusion, Centric↗
PubMedDate not supplied

[Occlusal plane].

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Dental Occlusion, Balanced↗