Nutricath insertion--a hazard.
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Catheterization, Peripheral↗
Biomedical subjects
P Latto
Publications and source records attributed to P Latto.
Effect on isoflurane anaesthesia and surgery on thyroid function in man.
The effect of isoflurane (Forane) anaesthesia and surgery on thyroid function was investigated in nine male patients. Isoflurane anaesthesia alone for 30 minutes prior to the start of surgery increased plasma triiodothyronine uptake (T3U) and thyroxine (T4) level by 18 and 20 per cent, respectively. Free thyroxine index (FTI) values in blood increased by 62 per cent during the same period. One hour of surgical procedure further elevated these parameters. Our data indicate that isoflurane anaesthesia and surgery increase circulating thyroxine in man.
Adult↗
Effect of isoflurane anaesthesia and surgery on carbohydrate metabolism and plasma cortisol levels in man.
The present study was undertaken to investigate in nine male surgical patients the effects of isoflurane anaesthesia alone on the carbohydrate metabolism by determining plasma growth hormone (GH), insulin, blood glucose, and cortisol, and to compare them with the effects of anaesthesia associated with surgical operations. Determination of plasma GH, insulin, cortisol, and blood glucose were made simultaneously before induction of isoflurane anaesthesia, after maintenance of anaesthesia for 15 minutes and 30 minutes and during and after conclusion of the operation. Plasma GH concentrations showed a significant elevation during isoflurane anaesthesia, and maintained a similar high level one hour after the start of the operation. An insignificant elevation in plasma insulin level and significant increases in blood glucose were noted during anaesthesia and operation. Plasma cortisol levels increased insignificantly during anaesthesia, but increased markedly during operation. Our observations would suggest that the increased blood level of GH and elevated blood cortisol play a part in the increase of blood glucose during isoflurane anaesthesia and surgical operations in man.
Adult↗
Kidney function after methoxyflurane analgesia during labour.
In a study of the effects of methoxyflurane on renal function, the urinary and blood urea concentrations, the urinary and plasma osmolalities, and the packed cell volume were studied in each of 50 mothers before and after delivery. Methoxyflurane 0.35% was used as an analgesic in 25 patients and the other 25 had 50% nitrous oxide and 50% oxygen (Entonox). There was no evidence of renal dysfunction in either group, nor were there any significant differences between the groups. In a further 200 mothers, of whom 100 had methoxyflurane and 100 had nitrous oxide analgesia, the urinary and blood urea concentrations were measured on the morning of discharge from hospital. There were no significant differences between the groups. These results suggest that methoxyflurane is not nephrotoxic when used as a self-administered analgesic.
Anesthesia, Inhalation↗