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Biomedical subjects

P Lauber

Publications and source records attributed to P Lauber.

9 recordsLinked to original sources
PubMed2000

[Clinical manifestations of CHARGE association in the area of the mouth, jaw and face].

Clinical experience of 11 patients with CHARGE association is reviewed. The study comprised six girls and five boys. All presented with congenital heart disease. Eight had bilateral choanal atresia. Coloboma affecting either one or both eyes was detected in nine children. Nine patients suffered abnormal pinnae or deafness. In addition to major abnormalities, further anomalies of the orofacial region and the upper airways occurred in all patients. All children exhibited velopharyngeal incoordination and swallowing problems often resulting in recurrent aspiration pneumonia. Three patients had cleft lip and palate. Both micrognathia and high-arched palate were present in two patients. Facial palsy was observed in six patients. Optimal management requires a multidisciplinary approach with active coordination and cooperation between the appropriate specialties. The anatomical repair of bilateral choanal atresia should be performed as early as possible. In our experience, the transpalatal approach is far more satisfactory than the transnasal. It gives the surgeon the opportunity of direct access and anatomical repair. After the child has grown stronger, a long-term management is desirable including developmental and feeding training.

Abnormalities, Multiple↗
PubMed1999

[Physical and psychological status of 60-70-year-old citizens of Bern with neurotic symptoms in childhood--a study over more than 50 years (Emmental cohort)].

The present study was undertaken to assess the influence of childhood variables (physical and emotional) to later well-being in a group of rural Swiss (Emmental Cohort). Our study is the first prospective cohort over a time period of more than 50 years. It includes 1537 children who were listed and assessed in 1942 (T1) because they had difficulties in school or were otherwise behaviorally disturbed. In 1995 (T2) more than 60% of the initial population could be reassessed by our study group. We found more subjects at T2 who had been rated as intelligent at T1. More subjects responding to T2 belonged to a higher social class, were more anxious, and had more psychosocial problems at T1. Social income at T2 is correlated to the social class at T1. More subjects have died since who were rated at T1 as being less intelligent, less neurotical, and having higher psychosocial problems. Twice as many men died than women. The emotional situation at T2 is significantly correlated to psychological well-being at T1. The somatic complaints at T2 correlate significantly to neurotic symptoms in childhood (T1). The more intelligent the children were rated at T1, the less emotional and somatic complaints were voiced at T2 and the better the psychic well-being was rated (T2). In addition, the former social milieu (T1) significantly determined somatic and psychological complaints at T2. Our data discern a significant correlation between actual status and former childhood variables more than 50 years later in a rural Swiss cohort (Emmental Cohort).

Adolescent↗
PubMed1998

Hospital pager systems may cause interference with pacemaker telemetry.

Electromagnetic interference (EMI) is a well-known cause of pacemaker dysfunction. The communication between pacemakers and programmers, enabled by telemetry, is also susceptible to EMI. We have observed that hospital pager systems have the potential to interfere with pacemaker telemetry. Measurements in our pacemaker clinic and in a technical laboratory have shown that inductive pager systems may disturb telemetry in the form of inaccurate battery voltage, current and impedance measurements, disturbances in intracardiac electrogram tracings, or total interruption of telemetric communications. The reason for EMI was an overlap of carrier frequencies of some pacemaker programmers (32-37 kHz) with those of our inductive pager system (36.11 kHz). Radiofrequency pager systems using higher frequencies (in MHZ range) are unlikely to cause such interference. Awareness of this interference potential may have practical implications in choosing the carrier frequencies of inductive hospital pager systems, as well as pacemaker programmers, and in planning the location of pacemaker clinics.

Electromagnetic Fields↗
PubMed1994

Cardiopulmonary exercise capacity in healthy normals of different age.

Sixty-nine healthy normals from the 3rd to the 6th decade were stressed to exhaustion by means of a cardiopulmonary exercise test on a bicycle ergometer. Peak VO2, VCO2 and ventilation differed significantly between the four decades: peak VO2 (mean +/- SD) was 3,393 +/- 516; 3,061 +/- 444; 2,817 +/- 801 and 2,589 +/- 687 ml/min (p < 0.001). The mean value for respiratory gas exchange ratio (R) at ventilatory threshold (VT) was 0.86 and for ventilatory equivalent O2 (EqO2) 0.24. Mean VO2 at VT was 1,662 +/- 521; 1,462 +/- 308; 1,474 +/- 559 and 1,268 +/- 232 ml/min (p < 0.05). The VO2 of the four age groups at VT was between 47 and 49% of peak VO2 (n.s.), and both parameters correlated significantly (r = 0.67, p < 0.001). The average increase of VO2 in relation to work rate (ml/W/min) was 11.5 +/- 1.2 for the total exercise and was below VT lower (9.4 +/- 1.9) than above VT (12.9 +/- 1.2) (p < 0.001).

Adult↗
PubMed1984

[What is the value of stable osteosynthesis of the distal radius?].

127 or 4% of the fractures of the distal radius seen in our department between 1968 and 1979 have been treated by internal fixation. 85 of these wrists could be reviewed after an average of 4.8 years. 70% of the fractures were multifragmentary and 87% involved the joint surface. In this difficult group correct length of the radius was restored in two thirds, and physiological angles of the joint in one third of the cases. In spite of frequent limitation of motion of the wrist joint, 80% of the patients were satisfied with the result. Careful selection of cases for internal fixation is necessary. It is indicated mainly in the Smith type fractures but may be replaced by percutaneous K-wire pinning, the external fixator or a delayed osteotomy.

Bone Plates↗