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Biomedical subjects

P Linneke

Publications and source records attributed to P Linneke.

17 recordsLinked to original sources
PubMed1989

[Reference values for progesterone, beta-HCG, estriol and human placental lactogen in the 10th-16th weeks of pregnancy].

Progesterone, beta-hCG, estriol and hPL in sera from 745 pregnant women have been measured in weeks 10 to 16 of pregnancy. The determined reference intervalls included the 10th and 90th percentile. All confidence intervalls have been calculated for a probability level of 10 per cent. The following levels were determined during the concerning weeks of pregnancy: progesterone 32-165 nmol/l, beta-hCG 31.5-260 micrograms/l, estriol 0.04-4.94 nmol l, and hPL 0.03-2.65 mg/l. The levels of progesterone are increasing weakly with the rising weeks of pregnancy, but the levels of beta-hCG are going down continuously. The levels estriol and hPL are showing a marked growth.

Chorionic Gonadotropin↗
PubMed1986

[No age dependence of biochemical parameters in pregnancy].

The parameters AFP, progesterone, HPL, estriol, SP1 and beta-HCG were evaluated in the sera of 994 pregnant women. The women were in the 5th to 25th weeks of pregnancy. Evaluation was carried out by means of radioimmunoassay and radial immunodiffusion. In collecting the data, we wished to determine whether there was a relationship between the age of the pregnant woman and the changes in parameter values during the course of the pregnancy. With the exception of beta-HCG concentrations, no age dependency was observed. However, the beta-HCG/age interrelationship was minor and without practical consequence.

Adolescent↗
PubMed1986

[Latex immunoassay].

The latex immunoassay can be considered a quickly practicable and simple methodic variant of the immunoassay. In this work principles and present capability of this assay are stated. Own experiments deal with the adsorption reaction of alkaline phosphatase and horseradish peroxidase at polystyrol respectively melanin formaldehyde lattices. The adsorption reaction of several lattices is partly extremely different. Problems concerning the construction of an assay useful for practical purposes are discussed.

Adsorption↗
PubMed1982

Isolation of human alpha-1 fetoprotein (AFP) from induced abortion material.

The isolation of alpha-1 fetoprotein (AFP) from material of an induced abortion is described. AFP is purified by anion exchange chromatography on DEAE-Sephadex A 50, affinity chromatography on Con-A-Sepharose, and preparative electrophoresis on agarose gel. The yield is about 10% of the original material. The purity was demonstrated by agarose gel electrophoresis and two-dimensional immunoelectrophoresis. The high concentration of AFP in material of induced abortion makes it particularly suitable for deriving human AFP.

Abortion, Legal↗
PubMed1975

[Diagnostic aspects of complex blood-protein analyses in screening].

During a screening at a testing of 5 different protein parameters (IgG, IgA, IgM, Hp, Tf) different types of distribution were found. While IgG, Hp and Tf have a normal distribution, IgG and IgM are not normally distributed in the uncleansed group. Measures of elimination of suggested sizes of influence ("liver parameters") remained without effect.

Blood Proteins↗