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Biomedical subjects

P Loche

Publications and source records attributed to P Loche.

4 recordsLinked to original sources

[Aspects and behavior of x-ray computed tomographic studies in subacute sclerosing panencephalitis].

The authors reports cerebral Computerized Axial Tomography findings examined, in association with other diagnostic tests, in 5 cases of Subacute Sclerosing Panencephalitis in the acute phase and repeated in 2 of these patients later, during the state and terminal phases of the disease. Hypodensity of the white matter was the main sign of initial cerebral parenchymal involvement and an atrophic aspect was most indicative of the terminal phase. Moreover, it has been shown that associated with clinical symptomatology, immunologic data and EEG signs, cerebral Computerized Axial Tomography may offer the possibility for evaluating the nature and the evolutive stage of the disease and facilitate differential diagnosis from other degenerative encephalopathies.

Child↗

[Cutaneous, radiologic and endocrinologic aspects of adrenoleukodystrophy].

A case of adrenoleucodistrophy in a 9 year old boy is reported. At onset, strabismo, skin hyperpigmentation, difficulty in deambulation and retarded writing and language capability were seen. The child's condition rapidly worsened. Normal hemochrome, urine tests, azotemia, blood calcium levels, alkaline phosphate, aminoaciduria and lipidogram values were found. EEG showed diffused slow activity mainly bilaterally at the anterior deviations. TAC revealed hypodense grey matter, especially in the parietal zone, a typical finding in leucodystrophy (Cattarossi e coll., 1981). Cellular biopsy showed modifications of the fibrocells, considered indicative of this condition. The study of the hypothalamic hypophyseal - adrenal - gonadal axis showed a significant increase of LH and RH after stimulation, increased testosterone and androstenedione and reduced basal plasma cortisol, and after stimulation, levels. These findings suggest that hyposurrenalism may be secondary to 21 - hydroxylase deficiency.

Biopsy↗

[Psychological aspects of the epileptic child and his relationship to his family environment].

Intellectual development and psychic problems were examined in thirty children, suffering from center - encephalic and focal epilepsy. Two parameters were taken into consideration: social insertion and family adaptation. Intellectual development was evaluated with the Terman-Merril test. At the same time, correlations between the epileptic form, the age of the onset of the seizures and their frequency, the precocity of therapeutic treatment were considered. The intellectual development and the personality were good in 23,7%, when the subjects were enclosed in valid familiar environment and when clinic disappearance of seizures was rapid; these aspects were compromised in 76,3%, when emotively valid family substractum was deficient and therapy was tardily started and barely efficient. On the basis of these data Authors affirm the importance of the precocity of therapy and the emotively valid substratum for preventing the behaviour disturbances in epileptic patients.

Adolescent↗

[Children and illness].

The authors examined the psychologic reaction on the behavior of 60 children, of 5 to 14 years, affected by acute or chronic illnesses, talking to them personally, and examining 80 free subject drawings made by the ill children. On the basis of the obtained data it is possible to state that every aspect of the disease acquires for the child a different meaning in connection with their own experience, and the psychic development stage and the emotional atmosphere, surrounding them.

Adolescent↗