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Biomedical subjects

P Lomholt

Publications and source records attributed to P Lomholt.

8 recordsLinked to original sources
PubMed1980

Circumclusion of atrial septal defect in elderly patients.

The results of surgical closure of atrial septal defect of secundum type (ASD) in 28 patients over 40 years of age with a closed method, circumclusion ad modum Søndergaard, are presented. One death occurred in the postoperative period caused by cerebral embolism in a patient with increased pressure in the pulmonary artery and atrial fibrillation. The most frequent postoperative complications were transient atrial arrhythmias and the post-pericardiotomy syndrome. The pressures in the pulmonary artery decreased in all patients, who had increased pressures pre-operatively. In two patients with pulmonary vascular resistance of 6 mmHg/l/min before operation the resistance was significantly reduced postoperatively. Residual shunts of less than 30% of the systemic flow were present in 4 cases. The ASD recurred years after the operation in two patients. At follow-up examinations on an average 44 months after operation, 75% had improved. In 20 cases the heart was reduced in size. In the remaining 6 the heart size was unchanged or larger, in spite of eliminated shunts in 5 of the 6 patients. Of 8 patients with atrial fibrillation before operation, two gained stable sinus rhythm postoperatively. It is concluded that circumclusion is also an effective method in the elderly patient with ASD and that such patients should undergo surgical repair of the defect.

Adult↗
PubMed1979

Congenital heart disease in the first month of life.

During the years 1963--73, 276 children with congenital heart disease were admitted to this hospital during their first month of life. Ventricular septal defect was the most common cardiac anomaly and this lesion, together with transposition of the great arteries, comprised 35% of all cardiovascular malformations. Extracardiac malformations were found in 86 patients. The cumulative survival rate for all patients was 66% in the first month of life and 33% in the first year. Forty-three patients were operated upon, but it is estimated from necropsy reports and available clinical data that another 74 patients, who died without operation, would have been suitable candidates for total corrective surgery.

Abnormalities, Multiple↗