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Biomedical subjects

P M Carter

Publications and source records attributed to P M Carter.

16 recordsLinked to original sources

Reduction of psychiatric inpatient stay for older adults by intensive case management.

An intensive case management program was offered for a 5-month period to all older persons admitted to a county inpatient unit. A quasiexperimental design was used for program evaluation with comparison to a preintervention baseline period and to younger adults on the inpatient unit during both baseline and intervention periods. Length of stay was reduced from 27 days during baseline to 12 days during intervention. For the younger patient group, length of stay changed from 11 to 12 days. Contrary to expectation, older patients were the young-old, mostly first admissions, and with mostly functional rather than organic diagnoses. This reduction in length of stay would save about $6,750 per geriatric admission.

Aged

The Australian reference preparation of human serum immunoglobulins.

An Australian Reference Preparation of human serum immunoglobulins was prepared from pooled sera of 240 healthy, adult donors. The preparation was calibrated for IgG, IgA and IgM levels by radial immunodiffusion against the 1st International Reference Preparation of Human Serum Immunoglobulins G, A and M (IgG, IgA and IgM) and for IgE by PRIST against the 1st International Reference Preparation of Human Serum Immunoglobulin E (IgE). The following potency values were assigned to the Australian Reference Preparation designated ASPS 78-1 (Lyoph.): 100 IU/vial for IgG and IgE, 102 IU/vial for IgA and 114 IU/vial for IgM.

Australia

Evaluation of the Gambro Lundia Major 1.36 m2 disposable parallel plate dialyzer.

The Gambro Lundia Major 1.36 m2 dialyzer was assessed in vivo in ten hemodialysis patients. Urea and creatinine clearances (measured as whole blood values at 60 minutes with a blood flow rate of 200 ml/minute) were 166 +/- 8 m/minute (mean +/- standard error of the mean, n = 9) and 115 +/- 4 ml/minute (n = 11). The creatinine clearance is 15% lower than in vitro data. There was a marked decrease in urea and creatinine clearance with third use of the dialyzer. The ultrafiltration rate was 490 ml/hour/100 mmHg. The priming volume was 125 ml (at a transmembrane pressure of 100 mmHg) and residual blood volume in the dialyzer was 0.57 +/- 0.11 ml (n = 5). The handling, storage and ease of disposal of the dialyzer is better than previous models and its performance characteristics are clinically acceptable.

Adult

IgM paraproteins.

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Amyloidosis

Lactic acidosis.

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Acidosis

Lactic acidosis.

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Acidosis

Clinical significance of 7s IgM in monoclonal IgM diseases.

The sera from 117 patients with diseases associated with a high production of monoclonal IgM were analysed for the presence of low molecular weight (7s) IgM by using a simple thin-layer Sephadex technique. 7s IgM was found in the sera of patients with myelomata (66%), lymphomata (45%), and Waldenström's macroglobulinaemia (20%), but was absent from the sera of patients with benign monoclonal macroglobulinaemia.This technique provides a cheap and practical test which may be valuable in selecting patients with lymphomata from those with benign lesions.

Adult

Cost-effectiveness of cervical cytologic examination during pregnancy.

BACKGROUND: We undertook a study to determine the cost-effectiveness of performing routine cervical cytologic examination during pregnancy. METHODS: The costs generated by doing routine prenatal cervical cytologic examination were calculated based on chart review in a family practice setting. A consecutive sample of 523 patients giving birth during 1990 was used. Analysis was done on 423 of those patients with prenatal Papanicolaou smear results recorded. Cost savings from detection of curable disease and utility of the test in terms of well-years saved were calculated from published statistics using a single-step Markov process to model the population at risk. RESULTS: For patients of all ages using a discount rate of 5 percent, the cost generated by prenatal cervical cytologic examination was $146,400 per well-year of life saved. Age stratification showed cost per well-year to range from $321,600 for patients aged 15 to 19 years to $48,800 for those aged 35 to 39 years. CONCLUSIONS: Routine prenatal cervical cytologic examination is significantly less cost-effective than the most commonly done medical procedures. If medical funding is limited, elimination of this test should be considered for women with normal findings on cervical cytologic examinations within the previous 2 to 3 years.

Adolescent