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Biomedical subjects

P M Falcone

Publications and source records attributed to P M Falcone.

7 recordsLinked to original sources
PubMed1996

Vitreomacular traction syndrome confused with pseudophakic cystoid macular edema.

Vitreomacular traction syndrome causes visual loss as a consequence of persistent traction on the fovea from an attached posterior hyaloid. The diagnosis can be challenging because the attachment may be subtle. Cystoid macular edema secondary to cataract extraction is well known and can occur in the absence of any surgical complication. Herein, a patient is described who had vitreomacular traction syndrome diagnosed after uneventful cataract surgery. Pars plana vitrectomy with detachment of the posterior hyaloid restored vision to an acceptable level. Careful examination and clinical suspicion are important because recognition and surgical intervention will benefit the majority of these patients.

Aged↗
PubMed1995

Roth spots seen on ophthalmoscopy: diseases with which they may be associated.

Roth spots seen on fundoscopic examination (white-centered hemorrhages) were classically described as septic emboli in patients with subacute bacterial endocarditis (SBE). Many physicians have considered them pathognomonic for this entity. More recent evidence suggests, however, that they are nonspecific and may be found in other disease states. A review of the pathogenesis of these white-centered hemorrhages will be provided, along with some diseases other than SBE in which they may occur.

Endocarditis, Subacute Bacterial↗
PubMed1993

Delayed onset of bilateral acute retinal necrosis syndrome: a 34-year interval.

The case is described of a male patient who had a history of acute retinal necrosis (ARN) OS at age 13 years. The eye subsequently had an inoperable retinal detachment with residual light perception visual acuity. After a 34-year disease-free interval, ARN developed OD that responded to medical treatment. This case represents the longest reported interval of ARN quiescence with eventual bilateral involvement and illustrates the importance of long-term patient follow-up.

Acyclovir↗
PubMed1993

Hydroxychloroquine toxicity despite normal dose therapy.

The risk of retinopathy associated with the use of hydroxychloroquine is said to be nullified if the dosage recommendations are followed strictly. In this case report, we describe an elderly patient with rheumatoid arthritis who had bilateral maculopathy, presumably secondary to hydroxychloroquine therapy, despite a dosing regimen within therapeutic guidelines. We believe special attention should be given to elderly patients who are being treated with hydroxychloroquine because their retinal pigment epithelium may be more susceptible to the toxic effects of this drug.

Aged↗
PubMed1993

Toxoplasmic papillitis as the initial manifestation of acquired immunodeficiency syndrome.

Toxoplasmic retinochoroiditis has been reported as the initial manifestation of acquired immunodeficiency syndrome (AIDS). Two authors have described two patients with AIDS and toxoplasmic papillitis. We report the case of a patient with a papillitis of unknown origin in whom the workup found systemic toxoplasmosis and subsequent positive human immunodeficiency virus status. To our knowledge, this is the first reported case of toxoplasmic papillitis as the initial manifestation of AIDS.

AIDS-Related Opportunistic Infections↗