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Biomedical subjects

P M Naidoo

Publications and source records attributed to P M Naidoo.

8 recordsLinked to original sources
PubMed1978

Cystinosis with Fanconi's syndrome. A case report.

A 19-year-old girl suffering from the nephropathic form of cystinosis presented with the full clinical and biochemical picture of Fanconi's syndrome. Polyuria, polydipsia and photophobia associated with severe growth retardation and rickets were the main clinical features. The essential biochemical abnormalities consisted of hypophosphataemia, hypokalaemia and hypo-uricaemia together with a systemic acidosis and a reduced creatinine clearance rate. There was generalized amino-aciduria, glycosuria and bicarbonaturia. In addition, the fractional excretion of potassium, phosphate and uric acid was significantly increased. Slit-lamp examination of the cornea and histological examination of the conjuctiva, liver, bone marrow and kidney demonstrated cystine crystals.

Acidosis, Renal Tubular↗
PubMed1976

Acute renal failure. Experience with 52 patients treated at Livingstone Hospital.

Fifty-two cases of acute renal failure at Livingstone Hospital were studied. Twenty-two cases were obstetric, 10 surgical and 20 medical. The aetiological factors are tabulated and the pathophysiology is reported. Clinical features and biochemical abnormalities are presented. Infection was the commonest associated factor, followed by hypotension and volume problems, coagulation disorders, jaundice and hepatic failure, respiratory failure, pancreatitis and typhoid fever. In 7 of the medical cases the aetiology was unknown and was assumed to be toxic. A case history of a patient with leptospirosis, acute renal failure, liver failure and pancreatitis is presented. The mortality in this series was 32%.

Acute Disease↗
PubMed1975

Typhoid polymyositis.

Four patients with typhoid polymyositis, 3 of whom were members of one family, are described. There was clinical, biochemical and histological evidence of severe muscle involvement which reversed on treatment with Chloromycetin. Muscle involvement in typhoid fever is a recognised pathological entity, but a clinical syndrome involving muscle has not previously been described.

Adolescent↗
PubMed1975

Fanconi's syndrome in an adult. A case history.

A case of the Fanconi syndrome in an adult presenting with life-threatening hypokalaemia is described. Amino-aciduria, glycosuria, high phosphate and uric acid clearances with reduced plasma levels of these two substances, reduced urinary concentrating power and abnormal urinary potassium loss with a systemic acidosis, were the essential biochemical abnormalities. Osteomalacia was shown by a radiological bone survey.

Adult↗
PubMed1974

Primary health care.

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Delivery of Health Care↗