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Biomedical subjects

P M Rinieris

Publications and source records attributed to P M Rinieris.

8 recordsLinked to original sources
PubMed1979

Affective disorders and ABO blood types.

Results of the present study provide evidence of: 1) a positive association between bipolar affective disorder and blood type O and a corresponding negative association between the former and blood type A, 2) a positive association between unipolar affective disorder and blood type O, and 3) a positive association between involutional depression and blood type A and a corresponding negative association between the former and blood types B and O. Sex does not appear to modify the ABO blood types' distribution in patients with bipolar, unipolar affective disorder, or involutional depression, and the same holds for early- or late-onset of the illness in patients with bipolar or unipolar affective disorders. Findings in the present study do not support the validity of the bipolar-unipolar distinction of affective disorders, and provide evidence in favour of the view that involutional depression is a genetically distinct nosological entity.

ABO Blood-Group System↗
PubMed1978

Obsessive-compulsive neurosis, anancastic symptomatology and ABO blood types.

Determinations of ABO blood types was carried out in 38 patients with obsessive-compulsive neurosis, 48 schizophrenics with anancastic symptomatology, 31 depressives with anancastic symptomatology, 260 schizophrenics free of anancastic symptomatology and 65 depressives free of anancastic symptomatology. Results were compared with a representative sample of the general population. The findings of the present study provide evidence of an association between obsessive-compulsive neurosis and phenotype A, whilst a similar association between ABO blood types and anancastic symptomatology occurring in the course of psychotic disorders was not found. The significance of these findings is discussed with regard to current diagnostic and aetiological issues in obsessive-compulsive neurosis.

ABO Blood-Group System↗
PubMed1978

Free-thyroxine index in psychotic and neurotic depression.

The mean free-thyroxine index value of a group of 25 psychotic depressive patients was found to be significantly lower than that of an age- and sex-matched group of 20 neurotic depressives (P less than 0.01). These findings support the view that psychotic and neurotic depression are differentiated not only with respect to their clinical expression, but also on account of their biological substrate. Comparison of free-thyroxine index values of each group of patients with a group of 240 euthyroid subjects hospitalized for various somatic illnesses revealed a lower mean free-thyroxine index value in the group of psychotic depressives (P less than 0.001). The neurotic depressives were not differentiated from the group of euthyroid subjects. The decreased thyroid activity in psychotic depression might be interpreted in the light of recent findings implicating catecholamines in both the release of hypothalamic hormones and the neurochemical mechanism of the affective disorders.

Adjustment Disorders↗
PubMedDate not supplied

Thyroid function in primary depression.

The thyroid function of 20 female inpatients with primary depression was investigated by the following tests: serum thyroxine, in vitro radioactive triiodothyronine uptake, free-thyroxine index, thyroidal 131I uptake and 48 hours protein-bound 131I. The mean values of serum thyroxine, free-thyroxine index and thyroidal 131I uptake of the patients were found decreased, compared to those of the euthyroid controls (to a statistically significant level for serum thyroxine and free-thyroxine index P less than .001). These findings point to a decreased thyroid activity in primary depression. The possibility of implication of a common neurochemical mechanism in both primary depression and thyroid hypoactivity was discussed.

Adult↗
PubMedDate not supplied

Side-effects of lithium.

An account of the side-effects of 30 patients treated with lithium at Athens University Department of Psychiatry during the last two years is presented. The most frequent side-effects were: tremor of bands, polydipsia, polyuria, increase in appetite, dryness of mouth, general muscular weakness and memory reduction. Most side-effects were infrequent, mild and in no case necessitated discontinuation of treatment.

Bipolar Disorder↗