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Biomedical subjects

P M Yuen

Publications and source records attributed to P M Yuen.

At least 91 records · Page 5Linked to original sources
PubMed1995

A comparison of laparotomy and laparoscopy in the management of ovarian masses.

To compare the results of laparoscopy with laparotomy in the management of ovarian masses not suspected of being malignant, a retrospective review was made of 115 patients with ovarian masses operated on, 50 by laparotomy and 65 by laparoscopy, in the Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Hong Kong, from November 1, 1992, to October 31, 1993. In the laparoscopy group, the average size of the ovarian masses was smaller, and there was a significant reduction in the intraoperative blood loss, postoperative analgesic requirement, morbidity (particularly febrile morbidity and urinary retention), length of hospital stay, and recuperation period. The incidence of rupture of the ovarian mass was not related to the operative approach but to the underlying pathology. Two patients in the laparoscopy group were converted to laparotomy, and 1 in the laparotomy group required a second laparotomy. The operating time was longer in the laparoscopic approach, but this could be reduced with experience and improved technique in specimen removal. Laparoscopy appears to be a better approach than laparotomy in the management of ovarian masses where malignancy is not suspected and a competent surgeon is available.

Adult↗
PubMed1995

A randomised double blind comparison of Syntometrine and Syntocinon in the management of the third stage of labour.

OBJECTIVE: To compare the effect of intramuscular Syntometrine and Syntocinon in the management of the third stage of labour. DESIGN: A randomised double blind prospective study. SETTING: Department of Obstetrics and Gynaecology, Prince of Wales Hospital, Hong Kong. SUBJECTS: One thousand consecutive patients with singleton pregnancy and vaginal delivery in February and March 1993. RESULTS: The use of Syntometrine in the management of the third stage not only reduced the blood loss after delivery but was associated with a 40% reduction in the risk of postpartum haemorrhage (odds ratio 0.60; 95% CI 0.21-0.88), and the need for repeat oxytocic injections (odds ratio of 0.63; 95% CI 0.44-0.89). The two drugs did not differ in their effect on the duration of the third stage. However, the incidence of manual removal of the placenta was higher when Syntometrine was used (odds ratio 3.7; 95% CI 1.03-12.5), although the overall incidence remained low. Side effects from both drugs, such as nausea, vomiting, headache and hypertension, were uncommon. CONCLUSION: Intramuscular Syntometrine is a better choice than Syntocinon in the management of the third stage of labour.

Adult↗
PubMed1995

Early incisional hernia following laparoscopic surgery.

Incisional hernia following laparoscopic surgery is seldom reported unless further complication arises and the presentation is usually late. A case of early incisional hernia following a laparoscopic ovarian cystectomy was reported. The hernia occurred through a 10/11 mm trocar port 3 days after the operation. Awareness of this clinical problem, its relationship to the site of abdominal entry, possible enlargement of the fascial defect during operation and hence the need of meticulous closure of the fascia when a large trocar is used will avoid such occurrence.

Adult↗
PubMed1995

Adenomyosis following endometrial rollerball ablation.

Two cases of adenomyosis following endometrial ablation using a rollerball electrode are reported. In both patients the endometrial ablation was performed for severe menorrhagia in the absence of uterine pathology. The endometrium was not prepared. After the operation, the women had persistent light menstruation for 7 to 9 months which then became heavy. They also developed progressive dysmenorrhoea and uterine enlargement. Abdominal hysterectomy was subsequently performed and adenomyosis was confirmed on histological examination. Prior endometrial preparation with hormone therapy may reduce the risk of incomplete destruction of the endometrium and therefore reduce the risk of postablation adenomyosis.

Adult↗
PubMed1994

Laparoscopic removal of retained surgical gauze after vaginal hysterectomy.

Surgical gauze was retained intraabdominally in a woman who had undergone a vaginal hysterectomy with anterior colporrhaphy. Laparoscopic removal was successfully performed with minimal risk or trauma to the patient. The integrity of the vaginal vault support was maintained and the need for a laparotomy avoided. The use of laparoscopy in vaginal hysterectomy should be considered as this offers the chance to assess the pelvis pre- and post-operatively and to remove the ovaries, where indicated.

Female↗
PubMed1994

Inversion (14)(q11q32) in childhood T-cell acute lymphoblastic leukemia.

Inversion (14)(q11q32) is a common cytogenetic aberration in T-cell chronic lymphoid malignancies but is rare in T-cell acute lymphoblastic leukemia (T-ALL). We describe two cases of childhood T-ALL in which inv(14)(q11q32) was present concomitantly with other karyotypic aberrations typical of T-ALL. The possible significance of inv(14) in these cases is also discussed.

Child↗
PubMed1994

A morphologic variant of May-Hegglin anomaly in a Chinese girl.

An 8 yr old Chinese girl was investigated for easy bruising and mild thrombocytopenia. Platelet aggregation studies and coagulation tests were found to be normal. The giant platelets and Döhle-like cytoplasmic inclusions in granulocytes confirmed the diagnosis of May-Hegglin anomaly. The father's granulocytes also had Döhle-like inclusions and one paternal aunt had a history of bleeding tendency. Review of literature showed that such Döhle-like inclusions had always been described morphologically as crescentic or spindle-shaped. In this case, however, the shape was roundish, oval or poorly defined. Ultrastructurally, the classic description was electron-dense long rods and needles orientating along the long axis of the "spindle". In this case, the only electron-dense particles were dot-like with a haphazard arrangement.

Asian People↗
PubMed1994

Laparoscopic management of ovarian masses: the initial experience and learning curve.

Fifty two consecutive patients undergoing laparoscopic surgery for ovarian masses were reviewed. The operative time depended on the experience of the surgeon and size of the tumour. It dropped progressively within the first 10 cases and then remained static until after 40 cases when there was a further decline. Postoperative pain was minimal and the median hospital stay was 2 days (range 1-7 days). The majority of patients returned to full activity within 2 weeks. The overall morbidity was 7.8% and was mild in nature without sequelae.

Adolescent↗
PubMed1994

Laparoscopic removal of ovarian cysts using a zipper storage bag.

Laparoscopic surgery has become increasingly popular in the management of pelvic masses. A major problem during laparoscopic surgery is removal of the specimen. The advantages of the bag retrieval technique using commercially available retrieval bag has been described. However, the size of the bags available is limited and they are relatively expensive. We describe the use of a zipper storage bag for the removal of ovarian cysts in 11 patients undergoing operative laparoscopy without spillage of the cyst contents, the need for abdominal wound extension or to perform a culdotomy. The operating time is reduced, compared to 'purpose designed' bag retrieval systems. This technique is safe, easy to perform and cost-effective.

Cost-Benefit Analysis↗
PubMed1993

Association between t(2;9)(p12;p23) and early B-precursor acute lymphoblastic leukemia.

We report the occurrence of t(2;9)(p12;p23) in a 20-month-old girl with early B-precursor acute lymphoblastic leukemia (ALL). This translocation has only been reported once before in an adult case of early B-precursor ALL with t(4;11)(q21;q23). We suggest that t(2;9)(p12;p23) may be associated with this particular phenotype of ALL.

Chromosomes, Human, Pair 2↗
PubMed1993

Laparoscopic removal of dermoid cysts using endopouch.

Laparoscopic oophorectomy was successfully performed in 6 patients with ovarian dermoid cysts. The use of Endopouch eliminates the risk of spillage and the need to extend the wound. The duration of operation ranged from 60 to 90 minutes and all patients were discharged within 48 hours with minimal pain and no complications.

Adult↗
PubMed1992

Comparison of antithrombin III, protein C and protein S levels in capillary and venous blood of newborn infants.

The plasma concentrations of antithrombin III, protein C and protein S in capillary and venous blood samples obtained simultaneously from 30 neonates were compared in order to determine the suitability of using capillary blood for estimation of these proteins with anticoagulant action. Our findings showed that while capillary and venous blood did not differ significantly in antithrombin III functional activity and protein C antigen levels, the capillary samples had significantly lower protein C functional activity and higher antithrombin III antigen level. Protein S antigen level was also significantly higher in the capillary samples although the difference was relatively small. The capillary and venous concentrations of the binding protein of protein S, C4b binding protein, were almost identical.

Antigens↗