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Biomedical subjects

P Madhok

Publications and source records attributed to P Madhok.

6 recordsLinked to original sources

Preventing a high rise in intraocular pressure after laser trabeculoplasty.

The high rise in pressure which sometimes follows laser trabeculoplasty is a serious and sight-threatening complication in patients with advanced glaucoma. In a previous study we found that patients undergoing laser trabeculoplasty were very unlikely to have a high rise in pressure if the initial pressure was less than 20 mmHg. In the present study a series of patients was given acetazolamide 500 mg immediately before laser trabeculoplasty if their pressures were greater than 20 mmHg. All patients were then monitored to see if this regime was effective in preventing a serious rise in intraocular pressure. Some of the patients with an initial pressure less than 20 mmHg still sustained a high rise in pressure after laser trabeculoplasty. A further series of patients was then given acetazolamide preoperatively and the postoperative rise in pressure was monitored two and 24 hours after trabeculoplasty. The acetazolamide prevented a high rise in pressure after laser trabeculoplasty in the majority of patients.

Acetazolamide↗

Abdominal tuberculosis in children.

Fifty cases of abdominal tuberculosis, seen over a 10-year period, are reviewed. A mass in the abdomen, with or without intestinal obstruction, was the commonest mode of presentation. Biochemical, haematological and bacteriological tests were of limited help in making a definite diagnosis, which was largely based on laparoscopic findings or on biopsy material obtained at operation. Laparoscopy was considered a simple, safe and reliable method for diagnosis, and it was at times possible to avoid a laparotomy. At operation, only the minimum of surgery was attempted. Division of bands, adhesiolysis, and conservative resection were performed, according to the intraoperative findings. Bypass operations are reserved for duodenal obstruction or extensively involved bowel. The prognosis was found to be excellent and the mortality negligible.

Child↗