Case report 306. Diagnosis: sarcoidosis affecting the frontal and nasal bones.
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Adult↗
Biomedical subjects
P Madoule
Publications and source records attributed to P Madoule.
[Osteoarticular lesions in Whipple's disease. Apropos of a destructive form and review of the literature].
A patient with Whipple's disease was considered as cured after treatment for two years, but relapse occurred as the neurological form. Radiographic imaging showed destructive osteoarticular lesions, with few or no symptoms, affecting the peripheral skeleton but also the sacroiliac joints. The published literature is reviewed and the different osteoarticular radiologic forms of the affection described.
Bone Diseases↗
[Intramural hematoma of the duodenum: x-ray computed tomographic aspect].
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Adult↗
Nuclear magnetic resonance imaging of facial structures.
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Adolescent↗
[Trichorhinophalangeal syndrome. Apropos of 4 cases discovered in adults].
Of four adult patients with the trichorhinophalangeal syndrome, 3 were from one family, one had associated major femoral trochlear dysplasia and bilateral mandibular condyle dysplasia, and another a bilateral coxa plana.
Adult↗
[Chronic osteitis and arthritis of palmoplantar pustulosis. A familial form of B-27 negative spondylarthropathy].
A 35-year old woman presented with pustulosis palmaris et plantaris evolving in acute episodes parallel to those of a rheumatic disease consisting of bilateral sacro-iliac arthritis, manubriosternal fusion and sterno-clavicular arthritis. Her brother had spondylitis compatible with the diagnosis of pustular osteo-arthritis though without pustulosis. He presented with bilateral sacro-iliac arthritis, manubriosternal fusion, sterno-clavicular arthritis and an ossified fragment detached from the antero-inferior angle of C6. The two patients had the same HLA phenotype: A1, A9, B5, B41, CW4, DR2, DR4, absence of B27. In a specimen from the sacro-iliac joint the authors found active bone remodelling and inflammatory osteitis with fibrosis and infiltrates rich in mononucleate cells. An electron microscopic study--to the authors' knowledge, the first to be performed in such cases--demonstrated intracytoplasmic filamentous inclusions in two macrophages of the synovial fringe. Only one other case of the familial form has been published so far. Like the rheumatism of acne conglobata, the spondylitis of pustulosis palmaris et plantaris is one of the causes of sterno-costo-clavicular hyperostosis.
Adult↗
Chemoembolization: principles and perspectives.
Chemoembolization is the injection of active-principle-bearing microparticles via selective catheterization. The authors discuss the advantages and the possibilities of this method in relation to selective catheterization and to the various time periods required for microparticle biodegradation and the kinetics of drug release. Particular attention is paid to intra-arterial chemoperfusion, chemoembolization and chemoinfusion with microparticles.
Capsules↗
[Comparative study of Hexabrix and Lipiodol UF in sialography].
Many new lipid- and water-soluble contrast media can be used in sialography, the three main criteria of choice being the cost, the quality of filling, particularly of the parenchyma, and its evacuation and clinical tolerance. Duroliopaque possesses very similar physicochemical properties to those of Lipiodol UF, but a sufficiently satisfactory filling of the parenchyma is not obtained. Comparison of Lipiodol UF and Hexabrix in parotid and submaxillary contrast imaging showed good clinical tolerance for both products, but improved parenchymatous filling with Lipiodol UF. However, the more effective glandular evacuation with Hexabrix makes this the product most suitable at the present time for morphologic exploration of salivary glands.
Contrast Media↗
[A study in dogs of micropellets for use in angiographic therapeutic procedures (author's transl)].
A study was conducted in dogs to evaluate the effect on the organism of a new embolisation material: carnauba wax micropellets. The ultimate objective was to study the possible use of micropellets containing an active product for therapy in situ. Renal embolisation was performed by selective or highly selective arterial catheterisation in dogs. Pathological examination demonstrated that only mild foreign body reactions occurred at the embolisation site. Overall tolerance was good. The micropellets were shown to possess some biodegradation properties and to be susceptible to deformation. An attempt is made to define the ideal micropellet from the point of view of size, kinetic features, and biodegradation properties.
Animals↗